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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
26.97
Human Site:
S446
Identified Species:
53.94
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
S446
S
F
F
S
R
Q
L
S
L
G
Q
G
S
Y
T
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
S446
S
F
F
S
R
Q
L
S
L
G
Q
G
S
Y
T
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
S446
S
F
F
S
R
Q
L
S
L
G
Q
G
S
Y
T
Dog
Lupus familis
XP_540860
463
51083
S445
S
F
F
S
R
Q
L
S
M
G
Q
G
S
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
S447
S
F
F
S
R
Q
L
S
S
S
Q
G
S
Y
T
Rat
Rattus norvegicus
Q5U2R3
466
51763
S447
S
F
F
S
R
Q
L
S
S
S
H
G
S
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
S454
S
F
F
S
R
Q
L
S
L
G
T
T
S
Y
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
R434
R
T
A
S
F
F
T
R
Q
N
T
H
N
Y
S
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
F449
K
P
K
R
A
A
S
F
F
T
R
Q
A
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
S429
G
S
F
T
N
K
L
S
K
F
T
L
A
T
F
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
G485
C
F
A
K
F
K
D
G
K
C
T
E
V
A
G
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
L477
S
K
M
D
R
L
C
L
S
T
F
S
N
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
86.6
N.A.
13.3
0
N.A.
N.A.
20
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
86.6
N.A.
26.6
13.3
N.A.
N.A.
40
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
9
0
0
0
0
0
0
17
9
0
% A
% Cys:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
67
67
0
17
9
0
9
9
9
9
0
0
0
9
% F
% Gly:
9
0
0
0
0
0
0
9
0
42
0
50
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
9
9
0
17
0
0
17
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
67
9
34
0
0
9
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
0
0
17
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
59
0
0
9
0
42
9
0
9
0
% Q
% Arg:
9
0
0
9
67
0
0
9
0
0
9
0
0
0
0
% R
% Ser:
67
9
0
67
0
0
9
67
25
17
0
9
59
0
9
% S
% Thr:
0
9
0
9
0
0
9
0
0
17
34
9
0
17
59
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _