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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
16.58
Human Site:
S460
Identified Species:
33.16
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
S460
T
V
V
Q
P
G
D
S
L
E
Q
G
_
_
_
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
S460
T
V
V
Q
P
G
D
S
L
E
Q
G
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
S460
T
V
V
Q
P
S
D
S
L
E
Q
G
_
_
_
Dog
Lupus familis
XP_540860
463
51083
S459
T
V
V
Q
P
T
D
S
L
E
Q
G
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
D461
T
V
V
Q
P
T
D
D
S
L
E
Q
S
_
_
Rat
Rattus norvegicus
Q5U2R3
466
51763
N461
T
V
V
Q
P
N
D
N
S
P
E
Q
G
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
G468
T
V
V
Q
P
T
D
G
L
E
Q
G
_
_
_
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
T448
S
A
V
Q
P
S
E
T
P
T
E
S
_
_
_
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
Q463
P
P
T
Y
S
A
V
Q
V
T
E
S
L
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
I443
F
D
D
E
G
R
C
I
G
Q
M
G
S
W
S
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
S499
G
S
F
K
A
F
Y
S
H
G
Q
T
L
_
_
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
P491
G
E
L
I
S
M
K
P
K
V
K
R
S
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
100
91.6
91.6
N.A.
46.1
46.1
N.A.
83.3
N.A.
25
0
N.A.
N.A.
6.6
15.3
0
P-Site Similarity:
100
100
91.6
91.6
N.A.
53.8
69.2
N.A.
83.3
N.A.
58.3
13.3
N.A.
N.A.
20
23
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
59
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
0
0
9
0
0
42
34
0
0
9
0
% E
% Phe:
9
0
9
0
0
9
0
0
0
0
0
0
0
9
0
% F
% Gly:
17
0
0
0
9
17
0
9
9
9
0
50
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
9
0
9
0
9
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
42
9
0
0
17
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
9
9
0
0
67
0
0
9
9
9
0
0
0
0
0
% P
% Gln:
0
0
0
67
0
0
0
9
0
9
50
17
0
0
9
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
9
0
0
17
17
0
42
17
0
0
17
25
0
9
% S
% Thr:
59
0
9
0
0
25
0
9
0
17
0
9
0
0
9
% T
% Val:
0
59
67
0
0
0
9
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
50
75
75
% _