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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD8
All Species:
27.58
Human Site:
Y183
Identified Species:
55.15
UniProt:
Q9BZ67
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZ67
NP_114110.1
464
51218
Y183
C
R
V
Q
L
G
P
Y
Q
P
G
R
P
A
A
Chimpanzee
Pan troglodytes
XP_001169593
464
51164
Y183
C
R
V
Q
L
G
P
Y
Q
P
G
H
P
A
A
Rhesus Macaque
Macaca mulatta
XP_001113750
464
51234
Y183
C
R
V
Q
L
G
P
Y
Q
P
G
Q
P
A
A
Dog
Lupus familis
XP_540860
463
51083
Y183
C
P
V
R
L
G
P
Y
L
P
G
L
P
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UFK8
466
51809
Y183
C
R
V
Q
L
G
P
Y
Q
P
G
Q
P
A
A
Rat
Rattus norvegicus
Q5U2R3
466
51763
Y183
C
R
V
Q
L
G
P
Y
Q
P
G
Q
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511109
472
52886
Y183
C
R
V
K
L
G
P
Y
R
P
G
Q
Q
T
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWP1
452
51566
Y181
C
R
L
E
L
G
P
Y
N
Q
N
E
H
T
P
Zebra Danio
Brachydanio rerio
XP_687842
471
52209
E184
C
A
I
E
L
G
T
E
L
D
D
Q
A
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393357
452
51555
E183
L
Q
G
R
Y
P
C
E
G
Q
A
R
Y
A
S
Nematode Worm
Caenorhab. elegans
NP_506340
504
56930
F237
F
C
L
Q
F
G
N
F
D
E
T
R
H
D
V
Sea Urchin
Strong. purpuratus
XP_001199223
505
57183
F219
A
F
L
E
Y
G
E
F
N
A
E
V
H
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.1
86.6
N.A.
87.5
86.6
N.A.
69.4
N.A.
59.2
55.2
N.A.
N.A.
29.5
23
29.7
Protein Similarity:
100
99.5
97.6
92.2
N.A.
92
91.1
N.A.
81.1
N.A.
73.4
68.5
N.A.
N.A.
46.5
41.2
48.1
P-Site Identity:
100
93.3
93.3
66.6
N.A.
93.3
93.3
N.A.
66.6
N.A.
40
20
N.A.
N.A.
13.3
20
6.6
P-Site Similarity:
100
93.3
100
73.3
N.A.
100
100
N.A.
86.6
N.A.
53.3
40
N.A.
N.A.
33.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
0
9
9
0
9
50
59
% A
% Cys:
75
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
9
9
0
0
9
0
% D
% Glu:
0
0
0
25
0
0
9
17
0
9
9
9
0
0
0
% E
% Phe:
9
9
0
0
9
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
92
0
0
9
0
59
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
25
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
25
0
75
0
0
0
17
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
9
0
17
0
9
0
0
0
0
% N
% Pro:
0
9
0
0
0
9
67
0
0
59
0
0
50
0
9
% P
% Gln:
0
9
0
50
0
0
0
0
42
17
0
42
9
9
0
% Q
% Arg:
0
59
0
17
0
0
0
0
9
0
0
25
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
9
0
0
25
9
% T
% Val:
0
0
59
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
67
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _