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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WHSC1L1 All Species: 24.24
Human Site: Y524 Identified Species: 59.26
UniProt: Q9BZ95 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZ95 NP_060248.2 1437 161613 Y524 K F I D Q F V Y S T K G I G N
Chimpanzee Pan troglodytes XP_519713 1437 161683 Y524 K F I D Q F V Y S T K G I G N
Rhesus Macaque Macaca mulatta XP_001091186 1439 161494 Y524 K F I D Q F V Y S T K G I G N
Dog Lupus familis XP_532803 1437 161676 Y524 K F I D Q F V Y S T K G I G N
Cat Felis silvestris
Mouse Mus musculus Q6P2L6 1439 160984 Y524 K F I D Q F V Y S T K G I G N
Rat Rattus norvegicus XP_001058474 1365 152585 K497 Q W S M L N E K Q K A R Y N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506476 1437 161653 Y522 K F I D Q F V Y S T K G V G N
Chicken Gallus gallus XP_001232891 1436 161286 T522 I D Q F V Y S T K G V G N K A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694414 1562 174797 S635 E L P K K T E S E E R P S S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT36 1427 159010 K523 P Y S D R L E K F Y Q T Y E N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.2 96.5 N.A. 91.7 44 N.A. 91.5 86.7 N.A. 57.6 N.A. 23.6 N.A. N.A. N.A.
Protein Similarity: 100 99.7 98.1 97.9 N.A. 95.2 59.5 N.A. 95.5 92.7 N.A. 70.5 N.A. 40 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 93.3 6.6 N.A. 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 13.3 N.A. 20 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 70 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 30 0 10 10 0 0 0 10 0 % E
% Phe: 0 60 0 10 0 60 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 70 0 60 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 60 0 0 0 0 0 0 0 0 0 50 0 0 % I
% Lys: 60 0 0 10 10 0 0 20 10 10 60 0 0 10 0 % K
% Leu: 0 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 10 10 70 % N
% Pro: 10 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 10 0 10 0 60 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 10 10 0 0 10 % R
% Ser: 0 0 20 0 0 0 10 10 60 0 0 0 10 10 0 % S
% Thr: 0 0 0 0 0 10 0 10 0 60 0 10 0 0 10 % T
% Val: 0 0 0 0 10 0 60 0 0 0 10 0 10 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 0 60 0 10 0 0 20 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _