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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
15.76
Human Site:
S1249
Identified Species:
28.89
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
S1249
R
A
P
L
S
S
C
S
E
L
Q
V
S
Q
F
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
T1185
L
K
Y
R
S
G
R
T
I
I
M
S
T
H
H
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
S1276
R
T
P
L
S
S
C
S
E
L
Q
V
S
Q
F
Dog
Lupus familis
XP_537788
2395
264756
A1236
Q
S
L
E
N
S
E
A
D
V
K
E
S
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
S1249
C
P
R
L
S
S
C
S
E
P
Q
V
S
Q
F
Rat
Rattus norvegicus
Q9ESR9
2434
270910
S1249
R
P
Q
L
S
N
C
S
E
M
Q
V
S
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S1145
D
V
D
S
S
L
S
S
C
R
N
S
S
S
T
Chicken
Gallus gallus
XP_422330
2276
256293
Y1155
N
C
F
G
S
G
F
Y
L
T
L
V
R
K
V
Frog
Xenopus laevis
NP_001089022
2363
267334
R1197
E
A
D
L
L
G
D
R
I
A
I
I
S
Q
G
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
T1147
L
S
A
S
S
C
R
T
S
S
S
T
V
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
G583
S
I
L
L
G
H
N
G
A
G
K
S
T
T
F
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
A792
F
P
P
T
S
G
T
A
K
I
Y
G
Q
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
L760
G
I
M
A
N
G
S
L
K
C
C
G
S
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
6.6
93.3
13.3
N.A.
73.3
73.3
N.A.
20
13.3
26.6
6.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
26.6
93.3
66.6
N.A.
73.3
86.6
N.A.
20
20
33.3
26.6
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
0
0
0
16
8
8
0
0
0
0
0
% A
% Cys:
8
8
0
0
0
8
31
0
8
8
8
0
0
0
0
% C
% Asp:
8
0
16
0
0
0
8
0
8
0
0
0
0
8
0
% D
% Glu:
8
0
0
8
0
0
8
0
31
0
0
8
0
0
0
% E
% Phe:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
39
% F
% Gly:
8
0
0
8
8
39
0
8
0
8
0
16
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
16
0
0
0
0
0
0
16
16
8
8
0
0
16
% I
% Lys:
0
8
0
0
0
0
0
0
16
0
16
0
0
8
8
% K
% Leu:
16
0
16
47
8
8
0
8
8
16
8
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
8
0
0
0
16
8
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
24
24
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
31
0
8
39
0
% Q
% Arg:
24
0
8
8
0
0
16
8
0
8
0
0
8
8
0
% R
% Ser:
8
16
0
16
70
31
16
39
8
8
8
24
62
24
0
% S
% Thr:
0
8
0
8
0
0
8
16
0
8
0
8
16
8
8
% T
% Val:
0
8
0
0
0
0
0
0
0
8
0
39
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _