Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 14.24
Human Site: S1275 Identified Species: 26.11
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 S1275 S D T S T E L S Y I L P S E A
Chimpanzee Pan troglodytes XP_001152577 2346 264166 L1211 A I I A Q G R L Y C S G T P L
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 S1302 S D T S T E L S Y I L P S E A
Dog Lupus familis XP_537788 2395 264756 G1262 P G E A P A G G L A R C T E L
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 S1275 S D T S T E L S Y I L P S E A
Rat Rattus norvegicus Q9ESR9 2434 270910 S1275 S D T S T E L S Y I L P S E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 L1171 Q S S S D A G L G S D H E S D
Chicken Gallus gallus XP_422330 2276 256293 C1181 S C G S Q C S C S C S S C A L
Frog Xenopus laevis NP_001089022 2363 267334 F1223 K N C F G T G F Y L T L V R R
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 G1173 S E S S S D A G L G S D H E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 Y609 G R I T I C G Y D V G N E P G
Sea Urchin Strong. purpuratus XP_798273 1913 213253 A818 G M C P Q H N A L F D K L T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 P786 L T L V K T S P T V S V A A H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 6.6 100 6.6 N.A. 100 100 N.A. 6.6 13.3 6.6 20 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 26.6 100 20 N.A. 100 100 N.A. 13.3 13.3 20 53.3 N.A. N.A. N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 16 0 16 8 8 0 8 0 0 8 16 31 % A
% Cys: 0 8 16 0 0 16 0 8 0 16 0 8 8 0 0 % C
% Asp: 0 31 0 0 8 8 0 0 8 0 16 8 0 0 8 % D
% Glu: 0 8 8 0 0 31 0 0 0 0 0 0 16 47 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % F
% Gly: 16 8 8 0 8 8 31 16 8 8 8 8 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 8 % H
% Ile: 0 8 16 0 8 0 0 0 0 31 0 0 0 0 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 8 0 8 0 0 0 31 16 24 8 31 8 8 0 24 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 8 0 0 8 8 0 0 8 0 0 0 31 0 16 0 % P
% Gln: 8 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 8 0 0 0 8 0 0 8 8 % R
% Ser: 47 8 16 54 8 0 16 31 8 8 31 8 31 8 8 % S
% Thr: 0 8 31 8 31 16 0 0 8 0 8 0 16 8 0 % T
% Val: 0 0 0 8 0 0 0 0 0 16 0 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 47 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _