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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
14.24
Human Site:
S1275
Identified Species:
26.11
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
S1275
S
D
T
S
T
E
L
S
Y
I
L
P
S
E
A
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
L1211
A
I
I
A
Q
G
R
L
Y
C
S
G
T
P
L
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
S1302
S
D
T
S
T
E
L
S
Y
I
L
P
S
E
A
Dog
Lupus familis
XP_537788
2395
264756
G1262
P
G
E
A
P
A
G
G
L
A
R
C
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
S1275
S
D
T
S
T
E
L
S
Y
I
L
P
S
E
A
Rat
Rattus norvegicus
Q9ESR9
2434
270910
S1275
S
D
T
S
T
E
L
S
Y
I
L
P
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
L1171
Q
S
S
S
D
A
G
L
G
S
D
H
E
S
D
Chicken
Gallus gallus
XP_422330
2276
256293
C1181
S
C
G
S
Q
C
S
C
S
C
S
S
C
A
L
Frog
Xenopus laevis
NP_001089022
2363
267334
F1223
K
N
C
F
G
T
G
F
Y
L
T
L
V
R
R
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
G1173
S
E
S
S
S
D
A
G
L
G
S
D
H
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Y609
G
R
I
T
I
C
G
Y
D
V
G
N
E
P
G
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
A818
G
M
C
P
Q
H
N
A
L
F
D
K
L
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
P786
L
T
L
V
K
T
S
P
T
V
S
V
A
A
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
6.6
13.3
6.6
20
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
26.6
100
20
N.A.
100
100
N.A.
13.3
13.3
20
53.3
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
16
8
8
0
8
0
0
8
16
31
% A
% Cys:
0
8
16
0
0
16
0
8
0
16
0
8
8
0
0
% C
% Asp:
0
31
0
0
8
8
0
0
8
0
16
8
0
0
8
% D
% Glu:
0
8
8
0
0
31
0
0
0
0
0
0
16
47
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
16
8
8
0
8
8
31
16
8
8
8
8
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
8
% H
% Ile:
0
8
16
0
8
0
0
0
0
31
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
8
0
0
0
31
16
24
8
31
8
8
0
24
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
8
8
0
0
8
0
0
0
31
0
16
0
% P
% Gln:
8
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
8
0
0
8
8
% R
% Ser:
47
8
16
54
8
0
16
31
8
8
31
8
31
8
8
% S
% Thr:
0
8
31
8
31
16
0
0
8
0
8
0
16
8
0
% T
% Val:
0
0
0
8
0
0
0
0
0
16
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
47
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _