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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 6.06
Human Site: S1420 Identified Species: 11.11
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 S1420 E V E A E A L S R V G Q G S R
Chimpanzee Pan troglodytes XP_001152577 2346 264166 G1356 V T E D S D S G P L F A G G A
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 S1447 E A E A E A L S R V G Q G S R
Dog Lupus familis XP_537788 2395 264756 G1406 H N Y T Q P R G N F I P Y A N
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 A1420 E A E M E A L A Q V G Q G S R
Rat Rattus norvegicus Q9ESR9 2434 270910 A1420 E A E M E A L A R V G Q G S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 L1313 E S R E T D L L S G M D G K G
Chicken Gallus gallus XP_422330 2276 256293 G1323 D T S R M P A G I A G D Q N E
Frog Xenopus laevis NP_001089022 2363 267334 D1372 S R T S L G V D N Q T T V I N
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 L1315 E S R E T D W L D G A D G K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 S751 G D W V F I M S H G K L V A S
Sea Urchin Strong. purpuratus XP_798273 1913 213253 Y960 K T T Y G D G Y H L T V V K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 K928 V I I T S V A K A F R L I V A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 13.3 93.3 0 N.A. 73.3 80 N.A. 20 6.6 0 13.3 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 20 93.3 13.3 N.A. 86.6 86.6 N.A. 20 20 13.3 13.3 N.A. N.A. N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 16 0 31 16 16 8 8 8 8 0 16 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 0 31 0 8 8 0 0 24 0 0 0 % D
% Glu: 47 0 39 16 31 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 16 8 0 0 0 0 % F
% Gly: 8 0 0 0 8 8 8 24 0 24 39 0 54 8 16 % G
% His: 8 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 8 0 0 8 0 8 0 8 8 0 % I
% Lys: 8 0 0 0 0 0 0 8 0 0 8 0 0 24 8 % K
% Leu: 0 0 0 0 8 0 39 16 0 16 0 16 0 0 0 % L
% Met: 0 0 0 16 8 0 8 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 16 0 0 0 0 8 16 % N
% Pro: 0 0 0 0 0 16 0 0 8 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 8 8 0 31 8 0 0 % Q
% Arg: 0 8 16 8 0 0 8 0 24 0 8 0 0 0 31 % R
% Ser: 8 16 8 8 16 0 8 24 8 0 0 0 0 31 8 % S
% Thr: 0 24 16 16 16 0 0 0 0 0 16 8 0 0 0 % T
% Val: 16 8 0 8 0 8 8 0 0 31 0 8 24 8 0 % V
% Trp: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _