Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 14.85
Human Site: S1603 Identified Species: 27.22
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 S1603 A P S D S P A S P D E D L Q A
Chimpanzee Pan troglodytes XP_001152577 2346 264166 Y1526 R E G W L P E Y P C G N S T P
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 S1630 A P S D S P A S L D E D P Q A
Dog Lupus familis XP_537788 2395 264756 T1576 V V T G D I L T D I T G H N V
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 S1603 A P S D S P V S P D E D S L Q
Rat Rattus norvegicus Q9ESR9 2434 270910 S1603 A P S D S P L S P D E D S L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 P1483 K K M L P V C P A G A G G L P
Chicken Gallus gallus XP_422330 2276 256293 P1493 H K K L T M L P E C P P G A G
Frog Xenopus laevis NP_001089022 2363 267334 N1551 V V S P S V T N I L L S Q E W
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 P1485 K K M L P E C P P G A G G L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 S921 S S T K S A D S Y Q K L M D S
Sea Urchin Strong. purpuratus XP_798273 1913 213253 F1130 H S R T L I S F S K K Y I Q M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 Y1098 M S S F D Q S Y Q S R Y G S I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 13.3 86.6 0 N.A. 73.3 73.3 N.A. 0 0 13.3 6.6 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 20 86.6 13.3 N.A. 73.3 73.3 N.A. 0 6.6 26.6 6.6 N.A. N.A. N.A. 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 0 0 0 8 16 0 8 0 16 0 0 8 16 % A
% Cys: 0 0 0 0 0 0 16 0 0 16 0 0 0 0 0 % C
% Asp: 0 0 0 31 16 0 8 0 8 31 0 31 0 8 0 % D
% Glu: 0 8 0 0 0 8 8 0 8 0 31 0 0 8 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 0 0 0 0 16 8 24 31 0 8 % G
% His: 16 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 8 8 0 0 8 0 8 % I
% Lys: 16 24 8 8 0 0 0 0 0 8 16 0 0 0 0 % K
% Leu: 0 0 0 24 16 0 24 0 8 8 8 8 8 31 8 % L
% Met: 8 0 16 0 0 8 0 0 0 0 0 0 8 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % N
% Pro: 0 31 0 8 16 39 0 24 39 0 8 8 8 0 24 % P
% Gln: 0 0 0 0 0 8 0 0 8 8 0 0 8 24 8 % Q
% Arg: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 24 47 0 47 0 16 39 8 8 0 8 24 8 8 % S
% Thr: 0 0 16 8 8 0 8 8 0 0 8 0 0 8 0 % T
% Val: 16 16 0 0 0 16 8 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 16 8 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _