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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 14.85
Human Site: S2023 Identified Species: 27.22
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 S2023 R P Q R M P V S T K P V E D D
Chimpanzee Pan troglodytes XP_001152577 2346 264166 V1957 K N L F A M V V E G V V Y F L
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 S2050 R P Q R M P V S T K P V E D D
Dog Lupus familis XP_537788 2395 264756 L1993 A S P V L L A L L I G I G D E
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 S2024 Q P Q R L P V S T K P V E D D
Rat Rattus norvegicus Q9ESR9 2434 270910 S2024 Q P Q R L P V S T K P V E D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 D1895 A K L P P V N D E D E D V R R
Chicken Gallus gallus XP_422330 2276 256293 S1905 W F A E T A K S P I I D E D E
Frog Xenopus laevis NP_001089022 2363 267334 P1989 G T W F A E P P K G S I D G E
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 E1897 T K L K P I G E E D E D V A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 R1333 L Q F K F V R R F L S Q V W T
Sea Urchin Strong. purpuratus XP_798273 1913 213253 V1542 P S A Y G I S V I N Q P M N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 P1510 M L S G E E T P T S G T A F I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 13.3 100 6.6 N.A. 86.6 86.6 N.A. 0 20 0 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 20 100 26.6 N.A. 100 100 N.A. 0 26.6 20 6.6 N.A. N.A. N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 16 0 16 8 8 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 16 0 24 8 47 31 % D
% Glu: 0 0 0 8 8 16 0 8 24 0 16 0 39 0 24 % E
% Phe: 0 8 8 16 8 0 0 0 8 0 0 0 0 16 0 % F
% Gly: 8 0 0 8 8 0 8 0 0 16 16 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 8 16 8 16 0 0 8 % I
% Lys: 8 16 0 16 0 0 8 0 8 31 0 0 0 0 8 % K
% Leu: 8 8 24 0 24 8 0 8 8 8 0 0 0 0 8 % L
% Met: 8 0 0 0 16 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 0 8 0 0 0 8 0 % N
% Pro: 8 31 8 8 16 31 8 16 8 0 31 8 0 0 0 % P
% Gln: 16 8 31 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 16 0 0 31 0 0 8 8 0 0 0 0 0 8 16 % R
% Ser: 0 16 8 0 0 0 8 39 0 8 16 0 0 0 0 % S
% Thr: 8 8 0 0 8 0 8 0 39 0 0 8 0 0 8 % T
% Val: 0 0 0 8 0 16 39 16 0 0 8 39 24 0 0 % V
% Trp: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _