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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 9.09
Human Site: S2326 Identified Species: 16.67
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 S2326 Q L K S E H I S L A Q V F S K
Chimpanzee Pan troglodytes XP_001152577 2346 264166 D2236 H L K S K F G D G Y I V T M K
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 S2353 Q L K S E H I S L A Q V F S K
Dog Lupus familis XP_537788 2395 264756 S2278 Q L Q S E H I S L A Q V F S K
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 H2325 Q Y Q L K S E H I S L A Q V F
Rat Rattus norvegicus Q9ESR9 2434 270910 H2325 Q Y Q L K S E H I S L A Q V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 K2158 A G S N P D L K P V Q E F F G
Chicken Gallus gallus XP_422330 2276 256293 K2168 T L K I K A P K T G M P P D P
Frog Xenopus laevis NP_001089022 2363 267334 A2252 I V T M K V R A S K P G F A P
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 E2160 A G A D P R L E P V M E F I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 N1596 E L K S L Y G N N Y T M T L S
Sea Urchin Strong. purpuratus XP_798273 1913 213253 D1805 D L G I T G G D A Y I N R D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 P1773 S T L V P P L P E E D V R F D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 33.3 100 93.3 N.A. 6.6 6.6 N.A. 13.3 13.3 6.6 6.6 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 40 100 100 N.A. 33.3 33.3 N.A. 26.6 20 33.3 20 N.A. N.A. N.A. 46.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 0 0 8 0 8 8 24 0 16 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 8 0 16 0 0 8 0 0 16 8 % D
% Glu: 8 0 0 0 24 0 16 8 8 8 0 16 0 0 8 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 47 16 16 % F
% Gly: 0 16 8 0 0 8 24 0 8 8 0 8 0 0 8 % G
% His: 8 0 0 0 0 24 0 16 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 16 0 0 24 0 16 0 16 0 0 8 0 % I
% Lys: 0 0 39 0 39 0 0 16 0 8 0 0 0 0 31 % K
% Leu: 0 54 8 16 8 0 24 0 24 0 16 0 0 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 16 8 0 8 0 % M
% Asn: 0 0 0 8 0 0 0 8 8 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 24 8 8 8 16 0 8 8 8 0 16 % P
% Gln: 39 0 24 0 0 0 0 0 0 0 31 0 16 0 0 % Q
% Arg: 0 0 0 0 0 8 8 0 0 0 0 0 16 0 0 % R
% Ser: 8 0 8 39 0 16 0 24 8 16 0 0 0 24 16 % S
% Thr: 8 8 8 0 8 0 0 0 8 0 8 0 16 0 0 % T
% Val: 0 8 0 8 0 8 0 0 0 16 0 39 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 8 0 0 0 24 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _