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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
13.64
Human Site:
Y518
Identified Species:
25
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
Y518
H
L
R
W
L
Q
Q
Y
V
A
E
L
R
L
H
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
P465
I
A
W
R
A
A
K
P
L
L
M
G
K
I
L
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
Y545
H
L
H
W
L
Q
Q
Y
V
A
E
L
R
L
H
Dog
Lupus familis
XP_537788
2395
264756
Y518
H
L
R
W
L
Q
Q
Y
V
A
E
L
R
L
H
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
Q517
Q
H
L
Q
W
L
Q
Q
Y
V
A
D
L
Q
L
Rat
Rattus norvegicus
Q9ESR9
2434
270910
Y518
H
L
H
W
L
Q
Q
Y
V
A
D
L
R
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
L440
E
D
S
Q
E
M
D
L
I
R
T
L
L
G
N
Chicken
Gallus gallus
XP_422330
2276
256293
I450
N
S
L
Q
M
N
M
I
R
D
S
L
K
H
S
Frog
Xenopus laevis
NP_001089022
2363
267334
L464
N
P
T
V
K
E
F
L
T
R
Q
L
G
D
E
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
R442
S
E
E
M
D
L
V
R
T
L
L
Q
N
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
T87
P
S
Q
T
P
I
I
T
P
Q
S
P
S
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
H55
D
T
T
I
H
P
A
H
S
N
I
D
K
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
0
93.3
100
N.A.
6.6
86.6
N.A.
6.6
6.6
6.6
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
26.6
93.3
100
N.A.
6.6
93.3
N.A.
20
26.6
26.6
0
N.A.
N.A.
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
0
0
31
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
8
0
0
8
8
16
0
16
0
% D
% Glu:
8
8
8
0
8
8
0
0
0
0
24
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% G
% His:
31
8
16
0
8
0
0
8
0
0
0
0
0
8
31
% H
% Ile:
8
0
0
8
0
8
8
8
8
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
0
0
0
24
0
0
% K
% Leu:
0
31
16
0
31
16
0
16
8
16
8
54
16
31
16
% L
% Met:
0
0
0
8
8
8
8
0
0
0
8
0
0
0
0
% M
% Asn:
16
0
0
0
0
8
0
0
0
8
0
0
8
8
8
% N
% Pro:
8
8
0
0
8
8
0
8
8
0
0
8
0
0
0
% P
% Gln:
8
0
8
24
0
31
39
8
0
8
8
8
0
8
0
% Q
% Arg:
0
0
16
8
0
0
0
8
8
16
0
0
31
0
0
% R
% Ser:
8
16
8
0
0
0
0
0
8
0
16
0
8
0
8
% S
% Thr:
0
8
16
8
0
0
0
8
16
0
8
0
0
0
16
% T
% Val:
0
0
0
8
0
0
8
0
31
8
0
0
0
8
0
% V
% Trp:
0
0
8
31
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _