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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLIS2
All Species:
31.21
Human Site:
S275
Identified Species:
68.67
UniProt:
Q9BZE0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZE0
NP_115964.2
524
55705
S275
E
G
C
N
K
R
Y
S
N
S
S
D
R
F
K
Chimpanzee
Pan troglodytes
XP_001137126
930
99492
S609
P
G
C
Q
K
A
F
S
N
S
S
D
R
A
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547148
557
59324
S308
E
G
C
N
K
R
Y
S
N
S
S
D
R
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDL9
521
55823
S275
E
G
C
N
K
R
Y
S
N
S
S
D
R
F
K
Rat
Rattus norvegicus
NP_001100448
521
55876
S275
E
G
C
N
K
R
Y
S
N
S
S
D
R
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514813
470
50041
I255
P
S
S
L
R
K
H
I
K
A
H
G
H
F
V
Chicken
Gallus gallus
P55879
663
73088
S342
E
G
C
N
K
A
F
S
N
A
S
D
R
A
K
Frog
Xenopus laevis
Q98T94
492
53940
S265
E
G
C
N
K
R
Y
S
N
S
S
D
R
F
K
Zebra Danio
Brachydanio rerio
Q1LYE3
623
67910
T332
E
G
C
G
R
S
F
T
T
S
N
I
R
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K0S9
384
44017
R180
S
E
R
G
F
N
A
R
Y
K
M
L
V
H
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34708
1110
122786
S318
A
D
C
E
K
A
F
S
N
A
S
D
R
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24
N.A.
90.6
N.A.
92.7
93.3
N.A.
74
25.4
64.3
20.2
N.A.
29.2
N.A.
20.6
N.A.
Protein Similarity:
100
33.5
N.A.
91.3
N.A.
94.6
95.2
N.A.
78.2
40.8
72.5
36.1
N.A.
39.1
N.A.
29
N.A.
P-Site Identity:
100
66.6
N.A.
100
N.A.
100
100
N.A.
6.6
73.3
100
33.3
N.A.
0
N.A.
53.3
N.A.
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
100
N.A.
33.3
86.6
100
60
N.A.
0
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
28
10
0
0
28
0
0
0
28
0
% A
% Cys:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
73
0
0
0
% D
% Glu:
64
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
37
0
0
0
0
0
0
55
0
% F
% Gly:
0
73
0
19
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
73
10
0
0
10
10
0
0
0
10
73
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
55
0
10
0
0
73
0
10
0
0
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
19
46
0
10
0
0
0
0
82
0
0
% R
% Ser:
10
10
10
0
0
10
0
73
0
64
73
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
46
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _