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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BARHL1 All Species: 21.52
Human Site: S259 Identified Species: 43.03
UniProt: Q9BZE3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZE3 NP_064448.1 327 35074 S259 A L Q R M F P S P Y F Y P Q S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118474 489 52159 S259 A L Q R M F P S P Y F Y P Q S
Dog Lupus familis XP_548404 505 52833 S437 A L Q R M F P S P Y F Y P Q S
Cat Felis silvestris
Mouse Mus musculus Q8VIB5 384 41441 S310 A L Q R M F P S P Y F Y H P S
Rat Rattus norvegicus P63156 327 35117 S259 A L Q R M F P S P Y F Y P Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507472 385 41941 S311 A P Q T M F P S P Y F Y H P S
Chicken Gallus gallus O57601 308 33768 R256 L S H A A A Q R I V R V P I L
Frog Xenopus laevis Q8JJ64 306 34004 I259 Q R I V R V P I L Y H E N S S
Zebra Danio Brachydanio rerio Q504H8 297 33069 V249 A A Q R I V R V P I L Y H E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24256 645 69932 G461 A F Q R L Y G G A T P Y L S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22910 260 28777 S213 T S S M I P A S N S Q N S L L
Sea Urchin Strong. purpuratus Q26656 405 44721 A334 I R A Q A N L A Q V S A V H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 66.4 64.3 N.A. 53.6 97.8 N.A. 53.2 29 26.6 26.9 N.A. 23.2 N.A. 33.3 24.4
Protein Similarity: 100 N.A. 66.4 64.3 N.A. 61.2 98.1 N.A. 61 42.5 42.8 42.2 N.A. 31.9 N.A. 47.4 36.5
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 100 N.A. 73.3 6.6 20 33.3 N.A. 26.6 N.A. 6.6 0
P-Site Similarity: 100 N.A. 100 100 N.A. 86.6 100 N.A. 73.3 6.6 20 53.3 N.A. 46.6 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 9 9 9 17 9 9 9 9 0 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % E
% Phe: 0 9 0 0 0 50 0 0 0 0 50 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 9 0 25 9 0 % H
% Ile: 9 0 9 0 17 0 0 9 9 9 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 42 0 0 9 0 9 0 9 0 9 0 9 9 17 % L
% Met: 0 0 0 9 50 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 9 0 0 9 9 0 9 % N
% Pro: 0 9 0 0 0 9 59 0 59 0 9 0 42 17 0 % P
% Gln: 9 0 67 9 0 0 9 0 9 0 9 0 0 34 0 % Q
% Arg: 0 17 0 59 9 0 9 9 0 0 9 0 0 0 0 % R
% Ser: 0 17 9 0 0 0 0 59 0 9 9 0 9 17 59 % S
% Thr: 9 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 9 0 17 0 9 0 17 0 9 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 59 0 67 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _