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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX2 All Species: 26.36
Human Site: T179 Identified Species: 52.73
UniProt: Q9BZI1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZI1 NP_001127694.1 471 49129 T179 L K K E N K M T W A P R N K S
Chimpanzee Pan troglodytes XP_526826 471 49121 T179 L K K E N K M T W A P R N K S
Rhesus Macaque Macaca mulatta XP_001084235 453 47887 E175 S E D E D E D E G D A A R S K
Dog Lupus familis XP_848580 472 49129 T178 L K K E N K M T W A P R N K S
Cat Felis silvestris
Mouse Mus musculus P81066 474 49466 T180 L K K E N K M T W A P R N K S
Rat Rattus norvegicus NP_001034594 474 49479 T180 L K K E N K M T W A P R N K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512003 628 67967 F339 L T Q V S T W F A N A R R R L
Chicken Gallus gallus Q9YGS0 485 52755 T206 L K K E N K M T W P P R N K C
Frog Xenopus laevis NP_001079235 455 49451 A177 K E N K M T W A P R N K S D D
Zebra Danio Brachydanio rerio NP_957351 432 46832 W154 T L T Q V S T W F A N A R R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24248 717 75403 T320 L K K E N K M T W E P K N R T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 P99 G G G P G P M P M F F S D A H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 84.2 96.4 N.A. 91.7 92.6 N.A. 48.4 32.9 72.4 64.9 N.A. 25.7 N.A. 28.8 N.A.
Protein Similarity: 100 99.7 87 97 N.A. 95.1 95.9 N.A. 54.4 45.1 80 72.4 N.A. 35.8 N.A. 40.1 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 13.3 86.6 0 6.6 N.A. 73.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 33.3 86.6 26.6 26.6 N.A. 93.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 9 50 17 17 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 0 9 0 9 0 0 9 0 0 9 9 9 % D
% Glu: 0 17 0 67 0 9 0 9 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 9 9 9 0 0 0 0 % F
% Gly: 9 9 9 0 9 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 59 59 9 0 59 0 0 0 0 0 17 0 50 9 % K
% Leu: 67 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 9 0 67 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 59 0 0 0 0 9 17 0 59 0 0 % N
% Pro: 0 0 0 9 0 9 0 9 9 9 59 0 0 0 0 % P
% Gln: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 59 25 25 9 % R
% Ser: 9 0 0 0 9 9 0 0 0 0 0 9 9 9 42 % S
% Thr: 9 9 9 0 0 17 9 59 0 0 0 0 0 0 9 % T
% Val: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 17 9 59 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _