KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX2
All Species:
14.85
Human Site:
T197
Identified Species:
29.7
UniProt:
Q9BZI1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZI1
NP_001127694.1
471
49129
T197
D
E
D
E
G
D
A
T
R
S
K
D
E
S
P
Chimpanzee
Pan troglodytes
XP_526826
471
49121
T197
D
E
D
E
G
D
A
T
R
S
K
D
E
S
P
Rhesus Macaque
Macaca mulatta
XP_001084235
453
47887
T193
P
D
K
A
Q
E
G
T
E
T
S
A
E
D
E
Dog
Lupus familis
XP_848580
472
49129
A196
D
E
D
E
G
D
A
A
R
S
K
G
E
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P81066
474
49466
S198
D
E
D
E
G
D
A
S
R
S
K
E
E
S
S
Rat
Rattus norvegicus
NP_001034594
474
49479
S198
D
E
D
E
G
D
A
S
R
S
K
E
E
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512003
628
67967
R357
N
K
M
T
W
A
P
R
N
K
S
E
D
E
D
Chicken
Gallus gallus
Q9YGS0
485
52755
E224
K
R
P
Y
E
E
E
E
E
E
E
E
E
C
S
Frog
Xenopus laevis
NP_001079235
455
49451
V195
D
E
G
D
G
E
R
V
K
E
E
Q
S
E
K
Zebra Danio
Brachydanio rerio
NP_957351
432
46832
P172
E
N
K
M
T
W
A
P
R
N
K
S
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24248
717
75403
D338
D
D
A
L
V
S
D
D
E
K
D
K
E
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
I117
H
P
Y
G
L
D
G
I
K
K
R
N
A
T
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
84.2
96.4
N.A.
91.7
92.6
N.A.
48.4
32.9
72.4
64.9
N.A.
25.7
N.A.
28.8
N.A.
Protein Similarity:
100
99.7
87
97
N.A.
95.1
95.9
N.A.
54.4
45.1
80
72.4
N.A.
35.8
N.A.
40.1
N.A.
P-Site Identity:
100
100
13.3
86.6
N.A.
80
80
N.A.
0
6.6
20
26.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
86.6
N.A.
93.3
100
N.A.
26.6
26.6
46.6
40
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
9
50
9
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
59
17
42
9
0
50
9
9
0
0
9
17
9
25
9
% D
% Glu:
9
50
0
42
9
25
9
9
25
17
17
34
75
17
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
50
0
17
0
0
0
0
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
9
9
17
0
0
0
0
0
17
25
50
9
0
0
9
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
9
9
0
9
0
9
0
% N
% Pro:
9
9
9
0
0
0
9
9
0
0
0
0
0
0
34
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
9
0
0
0
0
9
9
50
0
9
0
0
0
9
% R
% Ser:
0
0
0
0
0
9
0
17
0
42
17
9
9
34
17
% S
% Thr:
0
0
0
9
9
0
0
25
0
9
0
0
0
9
0
% T
% Val:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _