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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF3B All Species: 12.73
Human Site: S416 Identified Species: 25.45
UniProt: Q9BZI7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZI7 NP_075386.1 483 57762 S416 S T E S I G S S E K T E K K E
Chimpanzee Pan troglodytes XP_509755 451 51775 A385 D S G A P G E A M E R L G R V
Rhesus Macaque Macaca mulatta XP_001083072 483 57713 S416 S T E S I G S S E K T E K K E
Dog Lupus familis XP_851843 481 57417 S414 S T E S V G S S E K T E K K E
Cat Felis silvestris
Mouse Mus musculus NP_080849 472 57047 L405 N T E S I C S L E K I E K K E
Rat Rattus norvegicus NP_001129345 472 57045 L405 N T E S I C S L E K I E K K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509880 489 58405 S416 S T D F I G N S E K T D K V T
Chicken Gallus gallus XP_416933 538 62539 E457 H N Y S F T V E A V D K L G K
Frog Xenopus laevis O13024 873 101180 A647 I A E A K R L A E Q E R E R Q
Zebra Danio Brachydanio rerio B0S733 452 54077 P374 H H G Y S Y C P E T G D K L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624605 551 65167 E437 N I N K E T N E D N E S E E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780145 321 38755 D263 K G R D R D R D R E R E K E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.2 99.5 95 N.A. 84.6 85 N.A. 67.4 47.7 21.4 47.4 N.A. N.A. 33.7 N.A. 34.1
Protein Similarity: 100 54 99.5 97.5 N.A. 91.7 92.3 N.A. 82.6 62.2 33.5 64.5 N.A. N.A. 53.3 N.A. 48.4
P-Site Identity: 100 6.6 100 93.3 N.A. 73.3 73.3 N.A. 60 6.6 13.3 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 40 100 100 N.A. 80 80 N.A. 80 20 53.3 20 N.A. N.A. 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 0 0 0 17 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 17 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 9 0 9 0 9 9 0 9 17 0 0 0 % D
% Glu: 0 0 50 0 9 0 9 17 67 17 17 50 17 17 42 % E
% Phe: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 17 0 0 42 0 0 0 0 9 0 9 9 9 % G
% His: 17 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 42 0 0 0 0 0 17 0 0 0 0 % I
% Lys: 9 0 0 9 9 0 0 0 0 50 0 9 67 42 17 % K
% Leu: 0 0 0 0 0 0 9 17 0 0 0 9 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 25 9 9 0 0 0 17 0 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % Q
% Arg: 0 0 9 0 9 9 9 0 9 0 17 9 0 17 9 % R
% Ser: 34 9 0 50 9 0 42 34 0 0 0 9 0 0 0 % S
% Thr: 0 50 0 0 0 17 0 0 0 9 34 0 0 0 9 % T
% Val: 0 0 0 0 9 0 9 0 0 9 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 9 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _