KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRNKL1
All Species:
6.06
Human Site:
T790
Identified Species:
11.11
UniProt:
Q9BZJ0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZJ0
NP_057736.4
848
100452
T790
K
K
R
R
K
V
Q
T
D
D
G
S
D
A
G
Chimpanzee
Pan troglodytes
XP_514541
740
88757
L710
A
N
Q
P
N
L
K
L
L
A
M
A
K
L
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534328
687
83197
L657
A
N
Q
P
N
L
K
L
L
A
M
A
K
L
W
Cat
Felis silvestris
Mouse
Mus musculus
NP_080096
690
83397
M660
P
N
L
K
L
L
A
M
A
K
L
W
K
K
Q
Rat
Rattus norvegicus
P63155
690
83397
M660
P
N
L
K
L
L
A
M
A
K
L
W
K
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419315
686
83153
L656
A
N
Q
P
N
L
K
L
L
A
M
A
K
L
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957240
753
90709
E722
E
Y
D
D
R
D
D
E
D
E
S
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17886
702
84243
N672
M
W
K
T
Q
K
D
N
T
V
D
D
P
P
A
Honey Bee
Apis mellifera
XP_624146
682
82536
P652
P
E
D
E
S
Q
R
P
N
L
K
F
L
A
S
Nematode Worm
Caenorhab. elegans
NP_504547
744
87966
D714
R
E
G
D
S
D
T
D
L
S
E
S
S
S
S
Sea Urchin
Strong. purpuratus
XP_783739
1350
163700
T1304
K
K
R
R
K
I
Q
T
E
D
G
S
D
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12309
687
82427
D657
G
V
E
E
E
F
V
D
Y
I
F
P
D
D
I
Red Bread Mold
Neurospora crassa
Q7SGD2
695
82714
S665
Q
Q
T
K
N
L
S
S
L
L
A
M
A
N
A
Conservation
Percent
Protein Identity:
100
86.9
N.A.
78.4
N.A.
78
78
N.A.
N.A.
75.5
N.A.
69.9
N.A.
56.3
55.7
52
43.2
Protein Similarity:
100
87
N.A.
79.5
N.A.
79.5
79.5
N.A.
N.A.
78.5
N.A.
75.7
N.A.
68.2
67.4
67.2
52.3
P-Site Identity:
100
0
N.A.
0
N.A.
0
0
N.A.
N.A.
0
N.A.
13.3
N.A.
0
6.6
6.6
86.6
P-Site Similarity:
100
26.6
N.A.
26.6
N.A.
13.3
13.3
N.A.
N.A.
26.6
N.A.
40
N.A.
13.3
26.6
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
43.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.5
57.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
0
0
16
0
16
24
8
24
8
24
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
16
0
16
16
16
16
16
8
8
24
8
0
% D
% Glu:
8
16
8
16
8
0
0
8
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
16
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% I
% Lys:
16
16
8
24
16
8
24
0
0
16
8
0
39
16
0
% K
% Leu:
0
0
16
0
16
47
0
24
39
16
16
0
8
24
0
% L
% Met:
8
0
0
0
0
0
0
16
0
0
24
8
0
0
0
% M
% Asn:
0
39
0
0
31
0
0
8
8
0
0
0
0
8
0
% N
% Pro:
24
0
0
24
0
0
0
8
0
0
0
8
8
8
0
% P
% Gln:
8
8
24
0
8
8
16
0
0
0
0
0
0
0
16
% Q
% Arg:
8
0
16
16
8
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
16
0
8
8
0
8
8
31
16
16
24
% S
% Thr:
0
0
8
8
0
0
8
16
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
8
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
16
0
0
24
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _