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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRNKL1
All Species:
5.45
Human Site:
Y497
Identified Species:
10
UniProt:
Q9BZJ0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZJ0
NP_057736.4
848
100452
Y497
N
Y
D
A
W
F
D
Y
L
R
L
V
E
S
D
Chimpanzee
Pan troglodytes
XP_514541
740
88757
I430
K
R
Y
I
Y
L
W
I
N
Y
A
L
Y
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534328
687
83197
V377
K
R
Y
I
Y
L
W
V
N
Y
A
L
Y
E
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_080096
690
83397
A380
I
Y
L
W
V
N
Y
A
L
Y
E
E
L
E
A
Rat
Rattus norvegicus
P63155
690
83397
A380
I
Y
L
W
V
N
Y
A
L
Y
E
E
L
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419315
686
83153
I376
K
R
Y
I
Y
L
W
I
N
Y
A
L
Y
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957240
753
90709
P442
G
T
A
I
G
K
C
P
K
N
K
L
F
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17886
702
84243
Y392
A
E
R
T
R
Q
I
Y
K
T
C
L
E
L
I
Honey Bee
Apis mellifera
XP_624146
682
82536
I372
R
R
Y
I
Y
L
W
I
N
Y
A
L
F
E
E
Nematode Worm
Caenorhab. elegans
NP_504547
744
87966
D434
H
F
E
I
R
Q
L
D
L
N
A
A
R
K
I
Sea Urchin
Strong. purpuratus
XP_783739
1350
163700
Y371
N
Y
D
A
W
F
D
Y
L
R
L
M
E
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12309
687
82427
E377
Y
I
C
Y
V
E
L
E
L
E
N
S
L
L
E
Red Bread Mold
Neurospora crassa
Q7SGD2
695
82714
I385
E
E
R
E
T
K
D
I
G
R
A
R
Q
I
Y
Conservation
Percent
Protein Identity:
100
86.9
N.A.
78.4
N.A.
78
78
N.A.
N.A.
75.5
N.A.
69.9
N.A.
56.3
55.7
52
43.2
Protein Similarity:
100
87
N.A.
79.5
N.A.
79.5
79.5
N.A.
N.A.
78.5
N.A.
75.7
N.A.
68.2
67.4
67.2
52.3
P-Site Identity:
100
0
N.A.
0
N.A.
13.3
13.3
N.A.
N.A.
0
N.A.
0
N.A.
13.3
0
6.6
86.6
P-Site Similarity:
100
20
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
20
N.A.
6.6
N.A.
20
20
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
43.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.5
57.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
16
0
0
0
16
0
0
47
8
0
0
16
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
24
8
0
0
0
0
0
0
16
% D
% Glu:
8
16
8
8
0
8
0
8
0
8
16
16
24
47
39
% E
% Phe:
0
8
0
0
0
16
0
0
0
0
0
0
16
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
47
0
0
8
31
0
0
0
0
0
8
16
% I
% Lys:
24
0
0
0
0
16
0
0
16
0
8
0
0
16
0
% K
% Leu:
0
0
16
0
0
31
16
0
47
0
16
47
24
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
0
0
0
0
16
0
0
31
16
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
31
16
0
16
0
0
0
0
24
0
8
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
8
0
8
8
0
0
0
0
8
0
0
0
8
0
% T
% Val:
0
0
0
0
24
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
16
16
0
31
0
0
0
0
0
0
0
0
% W
% Tyr:
8
31
31
8
31
0
16
24
0
47
0
0
24
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _