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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A39 All Species: 27.88
Human Site: S346 Identified Species: 47.18
UniProt: Q9BZJ4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZJ4 NP_001137252.1 359 39215 S346 S T Y E F G K S F F Q R L N Q
Chimpanzee Pan troglodytes XP_001151221 359 39198 S346 S T Y E F G K S F F Q R L N Q
Rhesus Macaque Macaca mulatta XP_001114464 359 39101 S346 S T Y E F G K S F F Q R L N Q
Dog Lupus familis XP_548061 351 38452 S338 S T Y E F G K S F F Q R L N R
Cat Felis silvestris
Mouse Mus musculus Q9D8K8 359 39203 S346 S T Y E F G K S F F Q R L N Q
Rat Rattus norvegicus Q4V8K4 359 39217 S346 S T Y E F G K S F F H R L N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509035 405 45642 S359 A R T G D R G S Q P R R L L E
Chicken Gallus gallus
Frog Xenopus laevis Q6DFK2 341 37958 N334 S F F R K L N N E R Q L K S L
Zebra Danio Brachydanio rerio Q7SXW0 359 40094 T345 S T Y E F G K T F F Q E R N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623703 368 41596 R340 A T F E H G K R F F Q V Y N A
Nematode Worm Caenorhab. elegans Q09461 360 39995 K353 I S F Y E Y F K F L F Q K N H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 E293 A A C F L A Y E M T R S S L G
Baker's Yeast Sacchar. cerevisiae P53320 366 40745 K358 S S Y E I S K K V F G N K L H
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 G326 Y I R L G A A G P G R K E G V
Conservation
Percent
Protein Identity: 100 99.1 96.6 91.6 N.A. 88.5 88 N.A. 41.2 N.A. 48.1 58.5 N.A. N.A. 38.8 36.1 N.A.
Protein Similarity: 100 99.4 97.7 93.8 N.A. 93.3 93.5 N.A. 58.5 N.A. 64.6 73.8 N.A. N.A. 57.8 54.7 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 20 N.A. 13.3 73.3 N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 40 N.A. 33.3 80 N.A. N.A. 66.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25 34.4 26.7
Protein Similarity: N.A. N.A. N.A. 40.3 53.8 42.9
P-Site Identity: N.A. N.A. N.A. 0 33.3 0
P-Site Similarity: N.A. N.A. N.A. 13.3 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 0 0 0 15 8 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 65 8 0 0 8 8 0 0 8 8 0 8 % E
% Phe: 0 8 22 8 50 0 8 0 65 65 8 0 0 0 0 % F
% Gly: 0 0 0 8 8 58 8 8 0 8 8 0 0 8 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 15 % H
% Ile: 8 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 65 15 0 0 0 8 22 0 0 % K
% Leu: 0 0 0 8 8 8 0 0 0 8 0 8 50 22 15 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 8 0 0 0 8 0 65 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 58 8 0 0 36 % Q
% Arg: 0 8 8 8 0 8 0 8 0 8 22 50 8 0 8 % R
% Ser: 65 15 0 0 0 8 0 50 0 0 0 8 8 8 0 % S
% Thr: 0 58 8 0 0 0 0 8 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 58 8 0 8 8 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _