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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A39 All Species: 19.7
Human Site: S54 Identified Species: 33.33
UniProt: Q9BZJ4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZJ4 NP_001137252.1 359 39215 S54 A S E L M P S S R L W S L S Y
Chimpanzee Pan troglodytes XP_001151221 359 39198 S54 A S E L M P S S R L W S L S Y
Rhesus Macaque Macaca mulatta XP_001114464 359 39101 S54 A S E L T P S S R L W S L S Y
Dog Lupus familis XP_548061 351 38452 S54 A S E L M P P S R L W S L P Y
Cat Felis silvestris
Mouse Mus musculus Q9D8K8 359 39203 S54 T S E L T T P S R F W S L S Y
Rat Rattus norvegicus Q4V8K4 359 39217 S54 A S E L T T P S R F W S L S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509035 405 45642 Y58 P K G K C F V Y C N G L M D H
Chicken Gallus gallus
Frog Xenopus laevis Q6DFK2 341 37958 P50 R L Q A Q S K P F I K G K C F
Zebra Danio Brachydanio rerio Q7SXW0 359 40094 Q52 A Q Q T P L F Q A I A A E S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623703 368 41596 A52 V V K I R L Q A Q Q K A M L S
Nematode Worm Caenorhab. elegans Q09461 360 39995 Q67 V K I R L Q Q Q T R P F P K G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 A9 A D A W K D L A S G T V G G A
Baker's Yeast Sacchar. cerevisiae P53320 366 40745 D52 M I P D C S C D G A A E V P N
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 L42 L D V V K I R L Q L Q H H S L
Conservation
Percent
Protein Identity: 100 99.1 96.6 91.6 N.A. 88.5 88 N.A. 41.2 N.A. 48.1 58.5 N.A. N.A. 38.8 36.1 N.A.
Protein Similarity: 100 99.4 97.7 93.8 N.A. 93.3 93.5 N.A. 58.5 N.A. 64.6 73.8 N.A. N.A. 57.8 54.7 N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 66.6 73.3 N.A. 0 N.A. 0 13.3 N.A. N.A. 0 0 N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 66.6 73.3 N.A. 13.3 N.A. 20 33.3 N.A. N.A. 40 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25 34.4 26.7
Protein Similarity: N.A. N.A. N.A. 40.3 53.8 42.9
P-Site Identity: N.A. N.A. N.A. 6.6 0 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 8 8 0 0 0 15 8 8 15 15 0 0 8 % A
% Cys: 0 0 0 0 15 0 8 0 8 0 0 0 0 8 0 % C
% Asp: 0 15 0 8 0 8 0 8 0 0 0 0 0 8 0 % D
% Glu: 0 0 43 0 0 0 0 0 0 0 0 8 8 0 0 % E
% Phe: 0 0 0 0 0 8 8 0 8 15 0 8 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 0 8 8 8 8 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % H
% Ile: 0 8 8 8 0 8 0 0 0 15 0 0 0 0 0 % I
% Lys: 0 15 8 8 15 0 8 0 0 0 15 0 8 8 0 % K
% Leu: 8 8 0 43 8 15 8 8 0 36 0 8 43 8 8 % L
% Met: 8 0 0 0 22 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % N
% Pro: 8 0 8 0 8 29 22 8 0 0 8 0 8 15 0 % P
% Gln: 0 8 15 0 8 8 15 15 15 8 8 0 0 0 0 % Q
% Arg: 8 0 0 8 8 0 8 0 43 8 0 0 0 0 8 % R
% Ser: 0 43 0 0 0 15 22 43 8 0 0 43 0 50 8 % S
% Thr: 8 0 0 8 22 15 0 0 8 0 8 0 0 0 0 % T
% Val: 15 8 8 8 0 0 8 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 43 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 43 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _