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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A39 All Species: 12.12
Human Site: S66 Identified Species: 20.51
UniProt: Q9BZJ4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZJ4 NP_001137252.1 359 39215 S66 L S Y T K L P S S L Q S T G K
Chimpanzee Pan troglodytes XP_001151221 359 39198 F66 L S Y T K L P F S L Q S T G K
Rhesus Macaque Macaca mulatta XP_001114464 359 39101 S66 L S Y T K L P S S L Q S T G K
Dog Lupus familis XP_548061 351 38452 C66 L P Y A K W K C L L Y C N G V
Cat Felis silvestris
Mouse Mus musculus Q9D8K8 359 39203 S66 L S Y T K S S S A L Q S P G K
Rat Rattus norvegicus Q4V8K4 359 39217 S66 L S Y T K S P S T L Q S P G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509035 405 45642 E70 M D H M Y I C E E G S G R A W
Chicken Gallus gallus
Frog Xenopus laevis Q6DFK2 341 37958 G62 K C F V Y C N G L M D H L C M
Zebra Danio Brachydanio rerio Q7SXW0 359 40094 V64 E S R P W F R V T R P S K W K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623703 368 41596 L64 M L S N K C F L Y C N G L M D
Nematode Worm Caenorhab. elegans Q09461 360 39995 Y79 P K G E C F Y Y H N G L M E H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 V21 G G A A Q L V V G H P F D T I
Baker's Yeast Sacchar. cerevisiae P53320 366 40745 G64 V P N A V S S G S K M K T F T
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 L54 H S L S D P L L H Q R R A E I
Conservation
Percent
Protein Identity: 100 99.1 96.6 91.6 N.A. 88.5 88 N.A. 41.2 N.A. 48.1 58.5 N.A. N.A. 38.8 36.1 N.A.
Protein Similarity: 100 99.4 97.7 93.8 N.A. 93.3 93.5 N.A. 58.5 N.A. 64.6 73.8 N.A. N.A. 57.8 54.7 N.A.
P-Site Identity: 100 93.3 100 33.3 N.A. 73.3 80 N.A. 0 N.A. 0 20 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 100 93.3 100 33.3 N.A. 80 86.6 N.A. 20 N.A. 13.3 26.6 N.A. N.A. 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25 34.4 26.7
Protein Similarity: N.A. N.A. N.A. 40.3 53.8 42.9
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 22 0 0 0 0 8 0 0 0 8 8 0 % A
% Cys: 0 8 0 0 8 15 8 8 0 8 0 8 0 8 0 % C
% Asp: 0 8 0 0 8 0 0 0 0 0 8 0 8 0 8 % D
% Glu: 8 0 0 8 0 0 0 8 8 0 0 0 0 15 0 % E
% Phe: 0 0 8 0 0 15 8 8 0 0 0 8 0 8 0 % F
% Gly: 8 8 8 0 0 0 0 15 8 8 8 15 0 43 0 % G
% His: 8 0 8 0 0 0 0 0 15 8 0 8 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 15 % I
% Lys: 8 8 0 0 50 0 8 0 0 8 0 8 8 0 43 % K
% Leu: 43 8 8 0 0 29 8 15 15 43 0 8 15 0 0 % L
% Met: 15 0 0 8 0 0 0 0 0 8 8 0 8 8 8 % M
% Asn: 0 0 8 8 0 0 8 0 0 8 8 0 8 0 0 % N
% Pro: 8 15 0 8 0 8 29 0 0 0 15 0 15 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 36 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 0 0 8 8 8 8 0 0 % R
% Ser: 0 50 8 8 0 22 15 29 29 0 8 43 0 0 0 % S
% Thr: 0 0 0 36 0 0 0 0 15 0 0 0 29 8 8 % T
% Val: 8 0 0 8 8 0 8 15 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 8 % W
% Tyr: 0 0 43 0 15 0 8 8 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _