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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A39 All Species: 21.82
Human Site: T105 Identified Species: 36.92
UniProt: Q9BZJ4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZJ4 NP_001137252.1 359 39215 T105 F Q D P T R F T G T M D A F V
Chimpanzee Pan troglodytes XP_001151221 359 39198 T105 F Q D P T R F T G T M D A F V
Rhesus Macaque Macaca mulatta XP_001114464 359 39101 T105 F Q D P T R F T G T M D A F V
Dog Lupus familis XP_548061 351 38452 K105 G T M D A F V K I V R H E G T
Cat Felis silvestris
Mouse Mus musculus Q9D8K8 359 39203 T105 F Q D P T R F T G T L D A F V
Rat Rattus norvegicus Q4V8K4 359 39217 T105 F Q D P T R F T G T L D A F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509035 405 45642 P109 S L W S G L P P T L V M A V P
Chicken Gallus gallus
Frog Xenopus laevis Q6DFK2 341 37958 I101 Q I I R S E G I K S L W S G L
Zebra Danio Brachydanio rerio Q7SXW0 359 40094 S103 Y K T S T H F S G T L D A F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623703 368 41596 K103 D A L M K I S K N E G I L S L
Nematode Worm Caenorhab. elegans Q09461 360 39995 R118 D A I V K I A R H E G I R S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 E60 V K Q T V A S E G T K G L Y K
Baker's Yeast Sacchar. cerevisiae P53320 366 40745 N103 K N S S L K F N G T L E A F T
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 P93 G L W K G N I P A E L L Y V S
Conservation
Percent
Protein Identity: 100 99.1 96.6 91.6 N.A. 88.5 88 N.A. 41.2 N.A. 48.1 58.5 N.A. N.A. 38.8 36.1 N.A.
Protein Similarity: 100 99.4 97.7 93.8 N.A. 93.3 93.5 N.A. 58.5 N.A. 64.6 73.8 N.A. N.A. 57.8 54.7 N.A.
P-Site Identity: 100 100 100 0 N.A. 93.3 93.3 N.A. 6.6 N.A. 0 53.3 N.A. N.A. 0 0 N.A.
P-Site Similarity: 100 100 100 0 N.A. 100 100 N.A. 13.3 N.A. 33.3 80 N.A. N.A. 6.6 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25 34.4 26.7
Protein Similarity: N.A. N.A. N.A. 40.3 53.8 42.9
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 0
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 8 8 8 0 8 0 0 0 58 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 36 8 0 0 0 0 0 0 0 43 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 8 0 22 0 8 8 0 0 % E
% Phe: 36 0 0 0 0 8 50 0 0 0 0 0 0 50 0 % F
% Gly: 15 0 0 0 15 0 8 0 58 0 15 8 0 15 0 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 8 15 0 0 15 8 8 8 0 0 15 0 0 0 % I
% Lys: 8 15 0 8 15 8 0 15 8 0 8 0 0 0 8 % K
% Leu: 0 15 8 0 8 8 0 0 0 8 43 8 15 0 22 % L
% Met: 0 0 8 8 0 0 0 0 0 0 22 8 0 0 0 % M
% Asn: 0 8 0 0 0 8 0 8 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 36 0 0 8 15 0 0 0 0 0 0 8 % P
% Gln: 8 36 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 36 0 8 0 0 8 0 8 0 0 % R
% Ser: 8 0 8 22 8 0 15 8 0 8 0 0 8 15 8 % S
% Thr: 0 8 8 8 43 0 0 36 8 58 0 0 0 0 15 % T
% Val: 8 0 0 8 8 0 8 0 0 8 8 0 0 15 43 % V
% Trp: 0 0 15 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _