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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R12C All Species: 8.79
Human Site: S343 Identified Species: 27.62
UniProt: Q9BZL4 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZL4 NP_060077.1 782 84881 S343 S S S K H R R S S V C R L S S
Chimpanzee Pan troglodytes XP_001163082 977 108884 A471 T A G V T R S A S S P R L S S
Rhesus Macaque Macaca mulatta XP_001087036 805 87278 S366 C S S R H R R S S V C R L S S
Dog Lupus familis XP_865046 973 109668 K329 T L I I E P E K N A S R I E S
Cat Felis silvestris
Mouse Mus musculus Q3UMT1 782 84667 S347 S S S K H R R S S V C R L S S
Rat Rattus norvegicus Q10728 1032 115264 R441 A S W R L G L R K T G S Y G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90623 1004 111588 R436 A S W R L G L R K T G S Y G A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DRG7 1049 117303 A475 T A G V M R S A S S P R L S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.9 89.8 39.4 N.A. 87.2 37.4 N.A. N.A. 32.9 N.A. 36.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.7 90.8 53.9 N.A. 90 51.2 N.A. N.A. 48 N.A. 49.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 86.6 13.3 N.A. 100 6.6 N.A. N.A. 6.6 N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 93.3 33.3 N.A. 100 26.6 N.A. N.A. 26.6 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 25 0 0 0 0 0 25 0 13 0 0 0 0 25 % A
% Cys: 13 0 0 0 0 0 0 0 0 0 38 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 13 0 13 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 25 0 0 25 0 0 0 0 25 0 0 25 0 % G
% His: 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 13 0 0 0 0 0 0 0 0 13 0 0 % I
% Lys: 0 0 0 25 0 0 0 13 25 0 0 0 0 0 0 % K
% Leu: 0 13 0 0 25 0 25 0 0 0 0 0 63 0 0 % L
% Met: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 0 0 25 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 38 0 63 38 25 0 0 0 75 0 0 0 % R
% Ser: 25 63 38 0 0 0 25 38 63 25 13 25 0 63 75 % S
% Thr: 38 0 0 0 13 0 0 0 0 25 0 0 0 0 0 % T
% Val: 0 0 0 25 0 0 0 0 0 38 0 0 0 0 0 % V
% Trp: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _