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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R12C
All Species:
4.55
Human Site:
S450
Identified Species:
14.29
UniProt:
Q9BZL4
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZL4
NP_060077.1
782
84881
S450
P
G
A
G
L
Q
R
S
A
S
S
S
W
L
E
Chimpanzee
Pan troglodytes
XP_001163082
977
108884
L586
A
A
G
L
Q
K
S
L
L
S
S
T
S
T
T
Rhesus Macaque
Macaca mulatta
XP_001087036
805
87278
S473
P
G
A
G
L
Q
R
S
A
S
S
S
W
L
E
Dog
Lupus familis
XP_865046
973
109668
R529
R
T
S
S
S
Y
T
R
R
K
W
E
D
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMT1
782
84667
Q450
T
E
G
V
L
G
L
Q
R
S
A
S
S
S
L
Rat
Rattus norvegicus
Q10728
1032
115264
L587
A
G
L
Q
K
S
F
L
S
S
T
S
T
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90623
1004
111588
L585
S
A
G
L
Q
K
T
L
P
A
S
A
N
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRG7
1049
117303
H615
S
G
S
F
G
R
R
H
E
D
P
L
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
89.8
39.4
N.A.
87.2
37.4
N.A.
N.A.
32.9
N.A.
36.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.7
90.8
53.9
N.A.
90
51.2
N.A.
N.A.
48
N.A.
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
0
N.A.
20
20
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
6.6
N.A.
26.6
33.3
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
25
25
0
0
0
0
0
25
13
13
13
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
0
13
13
0
% D
% Glu:
0
13
0
0
0
0
0
0
13
0
0
13
0
0
25
% E
% Phe:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
38
25
13
13
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
25
0
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
13
25
38
0
13
38
13
0
0
13
0
25
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
25
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% P
% Gln:
0
0
0
13
25
25
0
13
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
13
38
13
25
0
0
0
0
0
0
% R
% Ser:
25
0
25
13
13
13
13
25
13
63
50
50
38
25
0
% S
% Thr:
13
13
0
0
0
0
25
0
0
0
13
13
13
38
38
% T
% Val:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
13
0
25
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _