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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHIA All Species: 26.36
Human Site: T235 Identified Species: 58
UniProt: Q9BZP6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZP6 NP_068569.2 476 52271 T235 L Y K Y P T D T G S N A Y L N
Chimpanzee Pan troglodytes XP_514112 466 51618 S235 L Y K R Q E E S G A A A S L N
Rhesus Macaque Macaca mulatta XP_001104487 474 52222 T235 L Y K Y P T D T G S N A Y L N
Dog Lupus familis XP_537030 493 53998 T245 L Y K Y P S D T G S N A Y L N
Cat Felis silvestris
Mouse Mus musculus Q91XA9 473 51985 T235 L Y K Y P T E T G S N A Y L N
Rat Rattus norvegicus Q6RY07 473 51933 T235 L Y K L P T E T G S N A Y L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518594 491 53993 S261 L Y K R K E E S G S A A E L T
Chicken Gallus gallus NP_989760 482 52220 T235 L Y K G P A D T G D L I Y F N
Frog Xenopus laevis NP_001085743 489 54190 F235 L C K G S K D F G D F Q Y F N
Zebra Danio Brachydanio rerio NP_998378 471 52576 E235 L Y Q G S K D E G D L I Y F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11174 617 66839 P270 L Y A T T E L P A E W N G W N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52 82.1 86.8 N.A. 81 82.3 N.A. 52.9 75 53.7 51 N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: 100 68.6 89.2 91.2 N.A. 90.1 91.1 N.A. 68.6 85.2 68 67.6 N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: 100 46.6 100 93.3 N.A. 93.3 86.6 N.A. 46.6 60 40 40 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 66.6 100 100 N.A. 100 93.3 N.A. 60 60 40 46.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 10 10 19 64 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 55 0 0 28 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 28 37 10 0 10 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 10 0 0 28 0 % F
% Gly: 0 0 0 28 0 0 0 0 91 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 0 0 82 0 10 19 0 0 0 0 0 0 0 0 0 % K
% Leu: 100 0 0 10 0 0 10 0 0 0 19 0 0 64 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 46 10 0 0 91 % N
% Pro: 0 0 0 0 55 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 10 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 19 10 0 19 0 55 0 0 10 0 0 % S
% Thr: 0 0 0 10 10 37 0 55 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % W
% Tyr: 0 91 0 37 0 0 0 0 0 0 0 0 73 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _