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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NMNAT2 All Species: 22.73
Human Site: T174 Identified Species: 45.45
UniProt: Q9BZQ4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZQ4 NP_055854.1 307 34439 T174 R P P V E R F T F V D E N A N
Chimpanzee Pan troglodytes XP_001158899 252 28306 D137 L K L L C G A D V L K T F Q T
Rhesus Macaque Macaca mulatta XP_001109387 426 47730 T293 R P P V E R F T F V D E N A N
Dog Lupus familis XP_853203 356 39538 T223 R P P V E R F T F V D E N A N
Cat Felis silvestris
Mouse Mus musculus Q8BNJ3 307 34486 T174 R P P V E R F T F V D E N A N
Rat Rattus norvegicus Q0HA29 307 34426 T174 R P P V E R F T F V D E N A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507826 272 31049 N157 D I T E I V S N Y G V V C V T
Chicken Gallus gallus XP_001234670 307 34456 T174 R P P M E R F T F V D E N A N
Frog Xenopus laevis NP_001091188 278 32072 G163 A D M L E S L G K P N L W K N
Zebra Danio Brachydanio rerio Q6PC93 304 34191 D174 M D R F T F V D E N A N L G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91851 223 25149 D108 V Q E K F G S D V G M M L V V
Sea Urchin Strong. purpuratus XP_783084 287 32645 E172 N A N Q L G V E V K L L C G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.9 71.8 81.1 N.A. 98.6 98 N.A. 22.7 93.4 29.6 86.6 N.A. N.A. N.A. 30.2 40.3
Protein Similarity: 100 47.5 71.8 83.9 N.A. 99 98.3 N.A. 38.7 97.3 45.5 92.8 N.A. N.A. N.A. 44.9 58.3
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 93.3 13.3 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 6.6 100 26.6 0 N.A. N.A. N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 9 0 0 0 9 0 0 50 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 17 0 0 % C
% Asp: 9 17 0 0 0 0 0 25 0 0 50 0 0 0 0 % D
% Glu: 0 0 9 9 59 0 0 9 9 0 0 50 0 0 0 % E
% Phe: 0 0 0 9 9 9 50 0 50 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 25 0 9 0 17 0 0 0 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 9 0 0 0 0 9 9 9 0 0 9 0 % K
% Leu: 9 0 9 17 9 0 9 0 0 9 9 17 17 0 0 % L
% Met: 9 0 9 9 0 0 0 0 0 0 9 9 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 9 0 9 9 9 50 0 59 % N
% Pro: 0 50 50 0 0 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 9 0 9 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 50 0 9 0 0 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 9 17 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 9 0 9 0 0 50 0 0 0 9 0 0 25 % T
% Val: 9 0 0 42 0 9 17 0 25 50 9 9 0 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _