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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMNAT2
All Species:
20
Human Site:
Y138
Identified Species:
40
UniProt:
Q9BZQ4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ4
NP_055854.1
307
34439
Y138
N
E
T
P
Q
P
I
Y
Q
N
S
N
V
A
T
Chimpanzee
Pan troglodytes
XP_001158899
252
28306
H101
V
K
V
L
R
H
H
H
S
E
L
L
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001109387
426
47730
Y257
N
E
T
P
Q
P
I
Y
Q
N
S
N
V
P
T
Dog
Lupus familis
XP_853203
356
39538
Y187
N
E
T
P
Q
P
I
Y
Q
N
S
N
V
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNJ3
307
34486
Y138
H
E
N
T
Q
P
I
Y
Q
N
S
N
V
P
T
Rat
Rattus norvegicus
Q0HA29
307
34426
Y138
H
E
N
T
Q
P
I
Y
Q
N
S
N
V
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507826
272
31049
E121
E
K
N
P
P
R
R
E
N
K
G
A
L
E
L
Chicken
Gallus gallus
XP_001234670
307
34456
Y138
N
E
S
T
Q
P
I
Y
Q
N
N
N
V
S
N
Frog
Xenopus laevis
NP_001091188
278
32072
R127
A
H
K
K
G
H
K
R
K
R
E
N
S
H
Q
Zebra Danio
Brachydanio rerio
Q6PC93
304
34191
Q138
N
E
T
S
A
I
Y
Q
N
T
V
N
K
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91851
223
25149
S72
V
R
A
A
T
K
S
S
D
W
I
R
A
D
D
Sea Urchin
Strong. purpuratus
XP_783084
287
32645
R136
P
T
R
R
G
T
K
R
R
R
N
L
R
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.9
71.8
81.1
N.A.
98.6
98
N.A.
22.7
93.4
29.6
86.6
N.A.
N.A.
N.A.
30.2
40.3
Protein Similarity:
100
47.5
71.8
83.9
N.A.
99
98.3
N.A.
38.7
97.3
45.5
92.8
N.A.
N.A.
N.A.
44.9
58.3
P-Site Identity:
100
0
93.3
93.3
N.A.
73.3
73.3
N.A.
6.6
66.6
6.6
26.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
26.6
93.3
100
N.A.
80
80
N.A.
20
86.6
13.3
33.3
N.A.
N.A.
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
9
0
0
0
0
0
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% D
% Glu:
9
59
0
0
0
0
0
9
0
9
9
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% G
% His:
17
9
0
0
0
17
9
9
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
9
50
0
0
0
9
0
0
0
0
% I
% Lys:
0
17
9
9
0
9
17
0
9
9
0
0
9
9
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
9
17
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
0
25
0
0
0
0
0
17
50
17
67
0
0
17
% N
% Pro:
9
0
0
34
9
50
0
0
0
0
0
0
0
25
9
% P
% Gln:
0
0
0
0
50
0
0
9
50
0
0
0
0
0
9
% Q
% Arg:
0
9
9
9
9
9
9
17
9
17
0
9
17
0
0
% R
% Ser:
0
0
9
9
0
0
9
9
9
0
42
0
9
34
0
% S
% Thr:
0
9
34
25
9
9
0
0
0
9
0
0
0
0
42
% T
% Val:
17
0
9
0
0
0
0
0
0
0
9
0
50
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _