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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
32.42
Human Site:
S506
Identified Species:
50.95
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
S506
W
L
S
T
T
N
Q
S
I
S
K
K
N
T
T
Chimpanzee
Pan troglodytes
XP_514054
932
104646
S506
W
L
S
T
T
N
Q
S
I
S
K
K
N
T
T
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
S506
W
L
S
T
T
N
Q
S
I
S
K
K
N
T
T
Dog
Lupus familis
XP_537162
933
104534
S507
W
L
S
T
T
N
Q
S
I
S
K
K
N
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
S507
W
L
S
T
T
N
R
S
I
S
K
K
N
T
T
Rat
Rattus norvegicus
XP_001070709
932
104212
N507
W
L
S
T
T
N
R
N
I
S
K
K
N
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
T586
W
L
S
T
T
N
Q
T
I
A
K
K
N
T
T
Chicken
Gallus gallus
XP_422293
1036
115091
T610
W
L
S
T
T
N
Q
T
I
S
K
K
N
T
T
Frog
Xenopus laevis
Q6GQB9
913
102717
S492
S
L
S
T
A
N
P
S
S
T
K
K
N
T
T
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
S482
S
L
S
T
A
S
N
S
P
A
P
P
V
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
K427
Q
V
G
K
K
A
L
K
T
L
Q
Q
H
A
K
Honey Bee
Apis mellifera
XP_624812
952
107871
N492
T
L
A
S
I
R
T
N
I
S
S
V
S
I
I
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
I481
S
I
G
H
K
E
K
I
E
N
K
I
N
P
R
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
A626
D
L
N
E
N
F
A
A
V
G
E
L
V
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
K422
Y
F
L
Y
R
A
T
K
D
P
F
Y
L
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
93.3
66.6
26.6
N.A.
0
20
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
73.3
40
N.A.
26.6
46.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
14
14
7
7
0
14
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
7
0
0
7
0
7
0
0
0
0
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
14
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
0
7
0
0
7
60
0
0
7
0
14
14
% I
% Lys:
0
0
0
7
14
0
7
14
0
0
67
60
0
0
7
% K
% Leu:
0
80
7
0
0
0
7
0
0
7
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
60
7
14
0
7
0
0
67
7
7
% N
% Pro:
0
0
0
0
0
0
7
0
7
7
7
7
0
7
0
% P
% Gln:
7
0
0
0
0
0
40
0
0
0
7
7
0
0
0
% Q
% Arg:
0
0
0
0
7
7
14
0
0
0
0
0
0
0
7
% R
% Ser:
20
0
67
7
0
7
0
47
7
54
7
0
7
0
0
% S
% Thr:
7
0
0
67
54
0
14
14
7
7
0
0
0
60
60
% T
% Val:
0
7
0
0
0
0
0
0
7
0
0
7
14
7
0
% V
% Trp:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _