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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
32.73
Human Site:
S544
Identified Species:
51.43
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
S544
N
D
P
L
Y
A
Q
S
I
R
E
P
L
K
N
Chimpanzee
Pan troglodytes
XP_514054
932
104646
S544
N
D
P
L
Y
A
Q
S
I
R
E
P
L
K
N
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
S544
N
D
P
L
Y
A
Q
S
I
R
E
P
L
K
N
Dog
Lupus familis
XP_537162
933
104534
S545
N
D
P
L
Y
A
Q
S
I
R
E
P
L
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
S545
N
D
P
L
Y
A
Q
S
I
R
E
P
L
K
N
Rat
Rattus norvegicus
XP_001070709
932
104212
S545
N
D
P
L
Y
A
Q
S
I
R
E
P
L
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
S624
N
D
P
M
Y
A
Q
S
I
R
E
P
L
K
N
Chicken
Gallus gallus
XP_422293
1036
115091
S648
N
D
P
M
F
A
Q
S
I
R
E
P
L
K
N
Frog
Xenopus laevis
Q6GQB9
913
102717
N530
N
D
P
M
Y
A
Q
N
I
R
E
P
L
K
N
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
F520
D
P
A
F
P
R
N
F
R
E
P
I
R
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
Y465
V
L
S
E
T
I
K
Y
L
F
L
L
F
S
D
Honey Bee
Apis mellifera
XP_624812
952
107871
V530
R
Q
P
L
R
N
M
V
E
D
V
Y
P
R
R
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
E519
K
L
P
T
E
R
E
E
A
Q
L
I
R
E
R
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
D664
R
G
E
C
M
F
V
D
K
A
R
H
L
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
D460
V
I
T
G
E
L
Q
D
R
M
E
T
F
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
86.6
0
N.A.
0
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
6.6
N.A.
20
20
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
60
0
0
7
7
0
0
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
60
0
0
0
0
0
14
0
7
0
0
0
0
7
% D
% Glu:
0
0
7
7
14
0
7
7
7
7
67
0
0
7
0
% E
% Phe:
0
0
0
7
7
7
0
7
0
7
0
0
14
0
0
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
0
7
0
0
60
0
0
14
0
0
0
% I
% Lys:
7
0
0
0
0
0
7
0
7
0
0
0
0
60
7
% K
% Leu:
0
14
0
47
0
7
0
0
7
0
14
7
67
0
7
% L
% Met:
0
0
0
20
7
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
7
7
7
0
0
0
0
0
0
60
% N
% Pro:
0
7
74
0
7
0
0
0
0
0
7
60
7
0
0
% P
% Gln:
0
7
0
0
0
0
67
0
0
7
0
0
0
7
0
% Q
% Arg:
14
0
0
0
7
14
0
0
14
60
7
0
14
7
14
% R
% Ser:
0
0
7
0
0
0
0
54
0
0
0
0
0
14
0
% S
% Thr:
0
0
7
7
7
0
0
0
0
0
0
7
0
0
0
% T
% Val:
14
0
0
0
0
0
7
7
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
54
0
0
7
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _