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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
23.03
Human Site:
S812
Identified Species:
36.19
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
S812
Q
P
S
S
E
N
D
S
Q
N
Q
S
G
E
Q
Chimpanzee
Pan troglodytes
XP_514054
932
104646
S812
Q
P
S
S
E
N
D
S
Q
N
Q
S
G
E
Q
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
S812
Q
P
S
S
E
N
D
S
Q
N
Q
S
A
E
Q
Dog
Lupus familis
XP_537162
933
104534
S813
Q
P
S
S
E
N
D
S
Q
N
Q
S
A
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
N811
E
D
Q
P
S
S
E
N
D
S
Q
N
Q
S
A
Rat
Rattus norvegicus
XP_001070709
932
104212
D812
D
Q
P
S
S
E
N
D
S
Q
N
Q
S
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
S893
Q
K
S
P
E
N
D
S
Q
N
Q
R
S
E
Q
Chicken
Gallus gallus
XP_422293
1036
115091
S917
Q
K
L
S
E
N
D
S
H
K
Q
N
S
E
E
Frog
Xenopus laevis
Q6GQB9
913
102717
S799
Q
K
P
V
E
N
D
S
Q
K
Q
A
L
E
D
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
Y754
L
L
E
A
L
K
E
Y
K
E
V
E
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
G694
K
V
L
V
A
E
R
G
D
C
T
F
V
S
K
Honey Bee
Apis mellifera
XP_624812
952
107871
V843
R
Q
M
K
E
F
F
V
N
H
I
Y
L
D
V
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
P818
I
L
H
N
L
D
Y
P
E
V
I
L
N
L
R
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
V948
L
L
D
A
L
G
D
V
P
K
E
T
I
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
E689
G
R
S
R
L
K
I
E
K
L
Q
I
Y
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
93.3
93.3
N.A.
6.6
6.6
N.A.
73.3
53.3
53.3
0
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
46.6
20
N.A.
73.3
66.6
60
20
N.A.
13.3
26.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
7
0
0
0
0
0
0
7
14
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
7
7
0
0
7
54
7
14
0
0
0
0
7
7
% D
% Glu:
7
0
7
0
54
14
14
7
7
7
7
7
0
47
14
% E
% Phe:
0
0
0
0
0
7
7
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
0
0
7
0
7
0
0
0
0
14
0
0
% G
% His:
0
0
7
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
14
7
7
0
7
% I
% Lys:
7
20
0
7
0
14
0
0
14
20
0
0
0
0
7
% K
% Leu:
14
20
14
0
27
0
0
0
0
7
0
7
14
14
7
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
47
7
7
7
34
7
14
7
7
0
% N
% Pro:
0
27
14
14
0
0
0
7
7
0
0
0
0
0
0
% P
% Gln:
47
14
7
0
0
0
0
0
40
7
60
7
7
7
34
% Q
% Arg:
7
7
0
7
0
0
7
0
0
0
0
7
0
0
14
% R
% Ser:
0
0
40
40
14
7
0
47
7
7
0
27
20
14
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% T
% Val:
0
7
0
14
0
0
0
14
0
7
7
0
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
7
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _