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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EDEM3 All Species: 22.73
Human Site: S824 Identified Species: 35.71
UniProt: Q9BZQ6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZQ6 NP_079467.3 932 104664 S824 G E Q I S S S S Q E V D L V D
Chimpanzee Pan troglodytes XP_514054 932 104646 S824 G E Q I S S S S Q E V D L V D
Rhesus Macaque Macaca mulatta XP_001113949 932 104559 S824 A E Q I S S S S Q E V D L V D
Dog Lupus familis XP_537162 933 104534 S825 A E Q I T S S S Q E V D L V D
Cat Felis silvestris
Mouse Mus musculus Q2HXL6 931 104181 S823 Q S A E Q M L S L S Q T V D L
Rat Rattus norvegicus XP_001070709 932 104212 L824 S A E Q M L P L P Q T V G L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516152 1013 112746 S905 S E Q I P E S S Q D L S L A K
Chicken Gallus gallus XP_422293 1036 115091 S929 S E E A S S A S Q D V G A V S
Frog Xenopus laevis Q6GQB9 913 102717 P811 L E D L F M T P E E I A E L L
Zebra Danio Brachydanio rerio XP_688275 861 96807 R766 V L L S D K A R D R D G A E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609611 801 90495 Q706 V S K A R L A Q K V G A A A L
Honey Bee Apis mellifera XP_624812 952 107871 S855 L D V K Q K T S L Q I R S F I
Nematode Worm Caenorhab. elegans NP_509671 931 106447 N830 N L R F N G I N Q D S D P R L
Sea Urchin Strong. purpuratus XP_001188495 1088 121533 Y960 I N R V V Q D Y I K L E N I R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38888 796 91227 D701 Y Q I D Y Y G D L I T A S T F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 97.3 N.A. 94.5 93.4 N.A. 80.8 76.4 78.6 69 N.A. 42.2 46.9 42.5 45.8
Protein Similarity: 100 99.6 99.2 98 N.A. 96.6 95.5 N.A. 85.7 81.8 86.5 80.6 N.A. 60.8 66.2 60.9 60.4
P-Site Identity: 100 100 93.3 86.6 N.A. 6.6 0 N.A. 46.6 46.6 13.3 0 N.A. 0 6.6 13.3 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 13.3 20 N.A. 60 66.6 46.6 13.3 N.A. 20 33.3 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 7 14 0 0 20 0 0 0 0 20 20 14 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 7 7 0 7 7 7 20 7 34 0 7 27 % D
% Glu: 0 47 14 7 0 7 0 0 7 34 0 7 7 7 7 % E
% Phe: 0 0 0 7 7 0 0 0 0 0 0 0 0 7 7 % F
% Gly: 14 0 0 0 0 7 7 0 0 0 7 14 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 7 34 0 0 7 0 7 7 14 0 0 7 7 % I
% Lys: 0 0 7 7 0 14 0 0 7 7 0 0 0 0 7 % K
% Leu: 14 14 7 7 0 14 7 7 20 0 14 0 34 14 27 % L
% Met: 0 0 0 0 7 14 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 7 0 0 7 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 7 0 7 7 7 0 0 0 7 0 0 % P
% Gln: 7 7 34 7 14 7 0 7 47 14 7 0 0 0 0 % Q
% Arg: 0 0 14 0 7 0 0 7 0 7 0 7 0 7 7 % R
% Ser: 20 14 0 7 27 34 34 54 0 7 7 7 14 0 7 % S
% Thr: 0 0 0 0 7 0 14 0 0 0 14 7 0 7 0 % T
% Val: 14 0 7 7 7 0 0 0 0 7 34 7 7 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 7 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _