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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
16.67
Human Site:
S839
Identified Species:
26.19
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
S839
Q
E
S
S
E
E
N
S
L
N
S
H
P
E
S
Chimpanzee
Pan troglodytes
XP_514054
932
104646
S839
Q
E
S
S
E
E
N
S
L
N
S
H
P
E
L
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
S839
Q
E
S
S
E
E
N
S
L
N
S
H
P
E
S
Dog
Lupus familis
XP_537162
933
104534
S840
Q
E
S
P
E
E
S
S
L
N
S
Q
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
H838
A
D
K
E
S
P
E
H
P
A
D
S
H
S
E
Rat
Rattus norvegicus
XP_001070709
932
104212
P839
D
Q
E
S
P
G
N
P
L
E
S
P
S
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
S920
P
E
P
V
G
E
N
S
L
V
S
E
P
D
P
Chicken
Gallus gallus
XP_422293
1036
115091
S944
E
E
P
E
E
G
E
S
S
D
V
S
D
L
D
Frog
Xenopus laevis
Q6GQB9
913
102717
P826
I
V
H
E
E
E
S
P
V
S
Q
P
E
V
P
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
R781
E
D
C
S
T
E
E
R
D
H
S
S
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
G721
I
V
C
D
N
V
P
G
S
S
G
E
T
Q
P
Honey Bee
Apis mellifera
XP_624812
952
107871
I870
L
E
S
Y
Y
N
W
I
V
K
S
R
N
E
D
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
H845
H
Q
E
I
V
E
R
H
V
T
E
L
Q
K
Y
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
P975
L
Q
Y
D
A
V
N
P
I
H
D
V
Q
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
I716
Q
D
V
S
R
K
D
I
F
S
N
A
C
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
93.3
100
80
N.A.
0
33.3
N.A.
46.6
20
13.3
26.6
N.A.
0
26.6
6.6
6.6
P-Site Similarity:
100
93.3
100
86.6
N.A.
6.6
40
N.A.
53.3
33.3
33.3
46.6
N.A.
13.3
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
0
0
7
0
7
0
7
7
% A
% Cys:
0
0
14
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
20
0
14
0
0
7
0
7
7
14
0
7
20
20
% D
% Glu:
14
47
14
20
40
54
20
0
0
7
7
14
7
40
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
14
0
7
0
0
7
0
0
0
0
% G
% His:
7
0
7
0
0
0
0
14
0
14
0
20
7
0
0
% H
% Ile:
14
0
0
7
0
0
0
14
7
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
0
7
0
0
0
7
0
0
0
7
0
% K
% Leu:
14
0
0
0
0
0
0
0
40
0
0
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
40
0
0
27
7
0
7
0
0
% N
% Pro:
7
0
14
7
7
7
7
20
7
0
0
14
40
0
34
% P
% Gln:
34
20
0
0
0
0
0
0
0
0
7
7
14
7
0
% Q
% Arg:
0
0
0
0
7
0
7
7
0
0
0
7
0
0
0
% R
% Ser:
0
0
34
40
7
0
14
40
14
20
54
20
7
7
20
% S
% Thr:
0
0
0
0
7
0
0
0
0
7
0
0
7
0
0
% T
% Val:
0
14
7
7
7
14
0
0
20
7
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _