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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
18.18
Human Site:
S848
Identified Species:
28.57
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
S848
N
S
H
P
E
S
L
S
L
A
D
M
D
N
A
Chimpanzee
Pan troglodytes
XP_514054
932
104646
S848
N
S
H
P
E
L
L
S
L
A
D
V
D
N
A
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
S848
N
S
H
P
E
S
L
S
P
A
D
M
D
N
A
Dog
Lupus familis
XP_537162
933
104534
S849
N
S
Q
P
E
S
S
S
P
T
D
T
D
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
S847
A
D
S
H
S
E
A
S
P
S
D
S
E
E
A
Rat
Rattus norvegicus
XP_001070709
932
104212
S848
E
S
P
S
E
P
P
S
P
A
D
S
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
S929
V
S
E
P
D
P
A
S
P
V
E
A
D
S
T
Chicken
Gallus gallus
XP_422293
1036
115091
L953
D
V
S
D
L
D
S
L
P
P
A
Q
A
D
T
Frog
Xenopus laevis
Q6GQB9
913
102717
S835
S
Q
P
E
V
P
S
S
D
S
P
S
G
G
D
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
E790
H
S
S
P
A
P
S
E
P
V
D
Q
S
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
F730
S
G
E
T
Q
P
M
F
A
M
S
G
D
G
K
Honey Bee
Apis mellifera
XP_624812
952
107871
K879
K
S
R
N
E
D
S
K
I
L
K
I
S
L
R
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
E854
T
E
L
Q
K
Y
L
E
F
K
D
A
D
Y
A
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
H984
H
D
V
Q
D
D
Q
H
I
A
Q
S
G
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
A725
S
N
A
C
D
A
V
A
S
L
Y
S
P
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
86.6
93.3
66.6
N.A.
20
40
N.A.
26.6
0
6.6
20
N.A.
6.6
13.3
26.6
6.6
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
33.3
46.6
N.A.
46.6
13.3
20
26.6
N.A.
26.6
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
7
7
14
7
7
34
7
14
7
0
47
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
7
20
20
0
0
7
0
54
0
47
7
7
% D
% Glu:
7
7
14
7
40
7
0
14
0
0
7
0
14
14
0
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
7
14
14
0
% G
% His:
14
0
20
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
14
0
0
7
0
0
0
% I
% Lys:
7
0
0
0
7
0
0
7
0
7
7
0
0
0
7
% K
% Leu:
0
0
7
0
7
7
27
7
14
14
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
14
0
0
0
% M
% Asn:
27
7
0
7
0
0
0
0
0
0
0
0
0
27
0
% N
% Pro:
0
0
14
40
0
34
7
0
47
7
7
0
7
0
0
% P
% Gln:
0
7
7
14
7
0
7
0
0
0
7
14
0
7
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
20
54
20
7
7
20
34
54
7
14
7
34
14
7
0
% S
% Thr:
7
0
0
7
0
0
0
0
0
7
0
7
0
7
14
% T
% Val:
7
7
7
0
7
0
7
0
0
14
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
7
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _