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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
21.82
Human Site:
S897
Identified Species:
34.29
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
S897
Q
S
E
T
E
E
D
S
N
P
N
V
S
W
G
Chimpanzee
Pan troglodytes
XP_514054
932
104646
S897
Q
S
E
T
E
E
D
S
N
P
N
V
S
W
G
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
S897
Q
S
E
T
E
E
D
S
N
P
N
V
S
W
G
Dog
Lupus familis
XP_537162
933
104534
S898
Q
S
E
T
E
E
D
S
N
P
N
V
S
W
G
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
S896
Q
S
E
T
E
E
D
S
S
P
N
V
S
W
G
Rat
Rattus norvegicus
XP_001070709
932
104212
P897
Q
P
E
T
E
E
D
P
S
P
N
V
S
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
S978
S
Q
T
E
E
D
S
S
P
A
V
P
W
D
K
Chicken
Gallus gallus
XP_422293
1036
115091
D1002
Q
Q
T
E
T
E
S
D
S
K
V
N
W
D
N
Frog
Xenopus laevis
Q6GQB9
913
102717
M884
E
D
S
T
E
E
K
M
D
N
K
V
Q
P
M
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
V839
E
D
S
N
N
Q
S
V
D
S
L
M
A
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
W779
Q
M
V
E
F
K
R
W
Q
L
A
K
E
Q
R
Honey Bee
Apis mellifera
XP_624812
952
107871
S928
I
H
K
E
S
V
L
S
D
N
D
F
Q
E
K
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
S903
K
T
K
P
I
P
P
S
V
F
A
R
L
P
G
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
Q1033
G
S
T
S
D
S
P
Q
S
G
S
H
I
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
G774
E
D
E
F
K
M
D
G
I
G
I
N
D
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
13.3
13.3
26.6
0
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
20
20
40
33.3
N.A.
13.3
26.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
14
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
7
7
47
7
20
0
7
0
7
20
0
% D
% Glu:
20
0
47
27
54
54
0
0
0
0
0
0
7
7
0
% E
% Phe:
0
0
0
7
7
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
7
0
14
0
0
0
0
47
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
0
% H
% Ile:
7
0
0
0
7
0
0
0
7
0
7
0
7
0
0
% I
% Lys:
7
0
14
0
7
7
7
0
0
7
7
7
0
0
14
% K
% Leu:
0
0
0
0
0
0
7
0
0
7
7
0
7
0
0
% L
% Met:
0
7
0
0
0
7
0
7
0
0
0
7
0
0
7
% M
% Asn:
0
0
0
7
7
0
0
0
27
14
40
14
0
0
7
% N
% Pro:
0
7
0
7
0
7
14
7
7
40
0
7
0
14
0
% P
% Gln:
54
14
0
0
0
7
0
7
7
0
0
0
14
7
7
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% R
% Ser:
7
40
14
7
7
7
20
54
27
7
7
0
40
7
7
% S
% Thr:
0
7
20
47
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
7
0
7
7
0
14
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
14
40
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _