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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EDEM3 All Species: 36.06
Human Site: S92 Identified Species: 56.67
UniProt: Q9BZQ6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZQ6 NP_079467.3 932 104664 S92 R V R G Q E P S R G D V D D A
Chimpanzee Pan troglodytes XP_514054 932 104646 S92 R V R G Q E P S R G D V D D A
Rhesus Macaque Macaca mulatta XP_001113949 932 104559 S92 R V R G Q E P S R G D V D D A
Dog Lupus familis XP_537162 933 104534 S93 R V R G Q E P S R G D V D D A
Cat Felis silvestris
Mouse Mus musculus Q2HXL6 931 104181 S93 R V R G Q E P S R G D V D D A
Rat Rattus norvegicus XP_001070709 932 104212 S93 R V R G Q E P S R G D V D D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516152 1013 112746 S172 R V R G Q E P S R G D V D D A
Chicken Gallus gallus XP_422293 1036 115091 S196 R V R G Q E P S R G D V D D A
Frog Xenopus laevis Q6GQB9 913 102717 S90 D D A L G K F S L T L I D T L
Zebra Danio Brachydanio rerio XP_688275 861 96807 L88 S L T L I D T L D T L A L L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609611 801 90495 Q40 T E T T M P T Q N M S N K E R
Honey Bee Apis mellifera XP_624812 952 107871 L88 R G D I D S T L G N F S L T L
Nematode Worm Caenorhab. elegans NP_509671 931 106447 L88 S V T L L D S L D T L V V M N
Sea Urchin Strong. purpuratus XP_001188495 1088 121533 Y122 H H G V M E W Y K D E L L Q M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38888 796 91227 Y35 T S K E L K A Y K Q E V K E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 97.3 N.A. 94.5 93.4 N.A. 80.8 76.4 78.6 69 N.A. 42.2 46.9 42.5 45.8
Protein Similarity: 100 99.6 99.2 98 N.A. 96.6 95.5 N.A. 85.7 81.8 86.5 80.6 N.A. 60.8 66.2 60.9 60.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 0 N.A. 0 6.6 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 26.6 13.3 N.A. 6.6 6.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 0 0 0 7 0 0 54 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 0 7 14 0 0 14 7 54 0 60 54 0 % D
% Glu: 0 7 0 7 0 60 0 0 0 0 14 0 0 14 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % F
% Gly: 0 7 7 54 7 0 0 0 7 54 0 0 0 0 0 % G
% His: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 7 0 0 14 0 0 14 0 0 0 14 0 0 % K
% Leu: 0 7 0 20 14 0 0 20 7 0 20 7 20 7 20 % L
% Met: 0 0 0 0 14 0 0 0 0 7 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 14 % N
% Pro: 0 0 0 0 0 7 54 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 54 0 0 7 0 7 0 0 0 7 0 % Q
% Arg: 60 0 54 0 0 0 0 0 54 0 0 0 0 0 7 % R
% Ser: 14 7 0 0 0 7 7 60 0 0 7 7 0 0 0 % S
% Thr: 14 0 20 7 0 0 20 0 0 20 0 0 0 14 0 % T
% Val: 0 60 0 7 0 0 0 0 0 0 0 67 7 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _