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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
31.82
Human Site:
T224
Identified Species:
50
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
T224
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Chimpanzee
Pan troglodytes
XP_514054
932
104646
T224
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
T224
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Dog
Lupus familis
XP_537162
933
104534
T225
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
T225
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Rat
Rattus norvegicus
XP_001070709
932
104212
T225
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
T304
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Chicken
Gallus gallus
XP_422293
1036
115091
T328
R
T
G
T
E
T
D
T
C
T
A
C
A
G
T
Frog
Xenopus laevis
Q6GQB9
913
102717
C214
E
T
D
T
C
T
A
C
A
G
T
M
I
L
E
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
E211
C
A
G
T
I
I
L
E
F
A
A
L
S
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
L163
A
H
I
L
A
E
Y
L
Q
K
H
A
D
T
M
Honey Bee
Apis mellifera
XP_624812
952
107871
C214
S
R
E
T
C
T
A
C
A
G
S
M
I
L
E
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
F211
G
G
T
M
I
L
E
F
A
A
L
T
S
L
T
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
L318
A
I
E
T
H
E
M
L
Y
Q
V
T
Q
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
L158
D
P
T
K
A
V
Y
L
G
D
D
Y
D
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
20
20
N.A.
0
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
20
26.6
N.A.
0
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
0
14
0
14
0
20
14
60
7
54
0
0
% A
% Cys:
7
0
0
0
14
0
0
14
54
0
0
54
0
0
0
% C
% Asp:
7
0
7
0
0
0
54
0
0
7
7
0
14
0
0
% D
% Glu:
7
0
14
0
54
14
7
7
0
0
0
0
0
0
14
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
7
% F
% Gly:
7
7
60
0
0
0
0
0
7
14
0
0
0
60
0
% G
% His:
0
7
0
0
7
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
0
7
7
0
14
7
0
0
0
0
0
0
14
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
7
7
20
0
0
7
7
0
20
0
% L
% Met:
0
0
0
7
0
0
7
0
0
0
0
14
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
0
7
0
0
% Q
% Arg:
54
7
0
0
0
0
0
0
0
0
0
0
0
14
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
7
0
14
0
7
% S
% Thr:
0
60
14
80
0
67
0
54
0
54
7
14
0
7
60
% T
% Val:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _