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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
40.91
Human Site:
T428
Identified Species:
64.29
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
T428
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Chimpanzee
Pan troglodytes
XP_514054
932
104646
T428
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
T428
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Dog
Lupus familis
XP_537162
933
104534
T429
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
T429
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Rat
Rattus norvegicus
XP_001070709
932
104212
T429
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
T508
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Chicken
Gallus gallus
XP_422293
1036
115091
T532
Y
Y
L
E
V
G
K
T
L
I
E
N
L
N
K
Frog
Xenopus laevis
Q6GQB9
913
102717
T414
Y
Y
L
E
V
G
K
T
L
I
D
N
L
N
K
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
T404
Y
Y
L
E
V
G
R
T
V
L
E
N
L
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
F350
F
M
D
S
L
L
A
F
W
P
G
L
Q
V
L
Honey Bee
Apis mellifera
XP_624812
952
107871
K414
Y
Y
L
G
V
G
R
K
V
L
K
S
L
Q
T
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
Q403
H
Y
L
H
V
A
K
Q
I
M
D
S
I
N
K
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
F527
P
R
L
K
A
A
E
F
V
P
G
N
P
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
V345
A
F
F
S
G
L
Q
V
L
A
G
D
L
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
73.3
N.A.
0
40
40
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
73.3
80
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
14
7
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
14
7
0
14
7
% D
% Glu:
0
0
0
67
0
0
7
0
0
0
60
0
0
0
0
% E
% Phe:
7
7
7
0
0
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
74
0
0
0
0
20
0
0
0
0
% G
% His:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
7
60
0
0
7
0
0
% I
% Lys:
0
0
0
7
0
0
67
7
0
0
7
0
0
0
67
% K
% Leu:
0
0
87
0
7
14
0
0
67
14
0
7
80
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
74
0
74
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
14
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
7
7
0
0
0
0
7
7
0
% Q
% Arg:
0
7
0
0
0
0
14
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
14
0
0
0
0
0
0
0
14
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
7
% T
% Val:
0
0
0
0
80
0
0
7
20
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
74
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _