KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
35.76
Human Site:
T512
Identified Species:
56.19
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
T512
Q
S
I
S
K
K
N
T
T
S
E
Y
T
E
L
Chimpanzee
Pan troglodytes
XP_514054
932
104646
T512
Q
S
I
S
K
K
N
T
T
S
E
Y
T
E
L
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
T512
Q
S
I
S
K
K
N
T
T
S
E
Y
T
E
L
Dog
Lupus familis
XP_537162
933
104534
T513
Q
S
I
S
K
K
N
T
T
S
E
Y
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
T513
R
S
I
S
K
K
N
T
T
S
E
Y
T
E
L
Rat
Rattus norvegicus
XP_001070709
932
104212
T513
R
N
I
S
K
K
N
T
T
S
E
Y
T
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
T592
Q
T
I
A
K
K
N
T
T
T
E
Y
T
E
L
Chicken
Gallus gallus
XP_422293
1036
115091
T616
Q
T
I
S
K
K
N
T
T
T
E
Y
T
E
L
Frog
Xenopus laevis
Q6GQB9
913
102717
T498
P
S
S
T
K
K
N
T
T
T
Q
Y
T
E
L
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
I488
N
S
P
A
P
P
V
I
N
S
V
I
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
A433
L
K
T
L
Q
Q
H
A
K
V
S
C
G
Y
A
Honey Bee
Apis mellifera
XP_624812
952
107871
I498
T
N
I
S
S
V
S
I
I
N
K
F
N
V
D
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
P487
K
I
E
N
K
I
N
P
R
R
M
I
L
R
A
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
V632
A
A
V
G
E
L
V
V
A
D
P
F
T
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
N428
T
K
D
P
F
Y
L
N
I
G
V
H
L
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
86.6
66.6
26.6
N.A.
0
13.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
33.3
N.A.
20
46.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
14
0
0
0
7
7
0
0
0
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% C
% Asp:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
0
7
0
7
0
0
0
0
0
54
0
7
67
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
7
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
60
0
0
7
0
14
14
0
0
14
0
0
0
% I
% Lys:
7
14
0
0
67
60
0
0
7
0
7
0
0
0
7
% K
% Leu:
7
0
0
7
0
7
7
0
0
0
0
0
14
7
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
14
0
7
0
0
67
7
7
7
0
0
7
0
0
% N
% Pro:
7
0
7
7
7
7
0
7
0
0
7
0
0
0
0
% P
% Gln:
40
0
0
0
7
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
14
0
0
0
0
0
0
0
7
7
0
0
0
7
0
% R
% Ser:
0
47
7
54
7
0
7
0
0
47
7
0
0
0
0
% S
% Thr:
14
14
7
7
0
0
0
60
60
20
0
0
67
0
0
% T
% Val:
0
0
7
0
0
7
14
7
0
7
14
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
60
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _