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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EDEM3 All Species: 32.42
Human Site: T81 Identified Species: 50.95
UniProt: Q9BZQ6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZQ6 NP_079467.3 932 104664 T81 A D E L M P L T C R G R V R G
Chimpanzee Pan troglodytes XP_514054 932 104646 T81 A D E L M P L T C R G R V R G
Rhesus Macaque Macaca mulatta XP_001113949 932 104559 T81 A D E L M P L T C R G R V R G
Dog Lupus familis XP_537162 933 104534 T82 A D E L M P L T C R G R V R G
Cat Felis silvestris
Mouse Mus musculus Q2HXL6 931 104181 T82 A D E L M P L T C R G R V R G
Rat Rattus norvegicus XP_001070709 932 104212 T82 A D E L M P L T C R G R V R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516152 1013 112746 T161 A D E L M P L T C R G R V R G
Chicken Gallus gallus XP_422293 1036 115091 T185 A D E L M P L T C R G R V R G
Frog Xenopus laevis Q6GQB9 913 102717 R79 I R G Q E P S R G D V D D A L
Zebra Danio Brachydanio rerio XP_688275 861 96807 L77 R G D V D D A L G K F S L T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609611 801 90495 C29 A M C I V V A C V L S T E T T
Honey Bee Apis mellifera XP_624812 952 107871 S77 C K G R Y R G S E P N R G D I
Nematode Worm Caenorhab. elegans NP_509671 931 106447 L77 R G D V D D V L G N F S V T L
Sea Urchin Strong. purpuratus XP_001188495 1088 121533 D111 G G H V A A L D L Q E H H G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38888 796 91227 A24 H V A C E D D A Y S F T S K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 97.3 N.A. 94.5 93.4 N.A. 80.8 76.4 78.6 69 N.A. 42.2 46.9 42.5 45.8
Protein Similarity: 100 99.6 99.2 98 N.A. 96.6 95.5 N.A. 85.7 81.8 86.5 80.6 N.A. 60.8 66.2 60.9 60.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 0 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 26.6 N.A. 20 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 0 7 0 7 7 14 7 0 0 0 0 0 7 0 % A
% Cys: 7 0 7 7 0 0 0 7 54 0 0 0 0 0 0 % C
% Asp: 0 54 14 0 14 20 7 7 0 7 0 7 7 7 0 % D
% Glu: 0 0 54 0 14 0 0 0 7 0 7 0 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % F
% Gly: 7 20 14 0 0 0 7 0 20 0 54 0 7 7 54 % G
% His: 7 0 7 0 0 0 0 0 0 0 0 7 7 0 0 % H
% Ile: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 7 0 0 0 0 0 0 0 7 0 0 0 7 0 % K
% Leu: 0 0 0 54 0 0 60 14 7 7 0 0 7 0 20 % L
% Met: 0 7 0 0 54 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 60 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 14 7 0 7 0 7 0 7 0 54 0 60 0 54 0 % R
% Ser: 0 0 0 0 0 0 7 7 0 7 7 14 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 54 0 0 0 14 0 20 7 % T
% Val: 0 7 0 20 7 7 7 0 7 0 7 0 60 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _