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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM3
All Species:
21.52
Human Site:
T873
Identified Species:
33.81
UniProt:
Q9BZQ6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZQ6
NP_079467.3
932
104664
T873
N
P
T
E
N
H
E
T
T
N
L
N
G
E
C
Chimpanzee
Pan troglodytes
XP_514054
932
104646
T873
N
P
T
E
N
H
E
T
T
N
L
N
G
E
C
Rhesus Macaque
Macaca mulatta
XP_001113949
932
104559
T873
N
P
T
E
N
H
E
T
T
N
L
N
G
E
C
Dog
Lupus familis
XP_537162
933
104534
T874
N
P
V
E
N
H
E
T
T
S
L
D
G
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q2HXL6
931
104181
T872
G
S
T
E
N
H
E
T
T
S
L
D
G
E
C
Rat
Rattus norvegicus
XP_001070709
932
104212
T873
S
P
T
E
T
Q
E
T
A
G
L
D
G
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516152
1013
112746
P954
P
P
E
T
Q
E
T
P
I
Q
E
P
E
C
T
Chicken
Gallus gallus
XP_422293
1036
115091
A978
S
I
P
G
P
G
E
A
G
A
P
E
P
A
C
Frog
Xenopus laevis
Q6GQB9
913
102717
E860
S
Q
E
H
K
T
E
E
T
E
H
S
P
K
D
Zebra Danio
Brachydanio rerio
XP_688275
861
96807
G815
E
S
V
Q
P
A
E
G
L
G
S
Y
V
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609611
801
90495
L755
Y
S
M
E
F
G
K
L
S
A
V
M
Q
R
R
Honey Bee
Apis mellifera
XP_624812
952
107871
S904
A
V
V
V
P
N
P
S
I
M
K
M
D
Q
L
Nematode Worm
Caenorhab. elegans
NP_509671
931
106447
N879
A
Y
G
A
L
D
L
N
V
E
N
S
K
L
L
Sea Urchin
Strong. purpuratus
XP_001188495
1088
121533
E1009
L
S
S
G
G
N
I
E
E
E
V
D
M
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
V750
I
L
P
R
H
G
S
V
Q
I
K
K
H
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
97.3
N.A.
94.5
93.4
N.A.
80.8
76.4
78.6
69
N.A.
42.2
46.9
42.5
45.8
Protein Similarity:
100
99.6
99.2
98
N.A.
96.6
95.5
N.A.
85.7
81.8
86.5
80.6
N.A.
60.8
66.2
60.9
60.4
P-Site Identity:
100
100
100
80
N.A.
73.3
60
N.A.
6.6
13.3
13.3
6.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
73.3
N.A.
6.6
20
33.3
13.3
N.A.
26.6
20
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
0
7
0
7
7
14
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
47
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
27
7
7
7
% D
% Glu:
7
0
14
47
0
7
60
14
7
20
7
7
7
40
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
14
7
20
0
7
7
14
0
0
40
0
0
% G
% His:
0
0
0
7
7
34
0
0
0
0
7
0
7
0
0
% H
% Ile:
7
7
0
0
0
0
7
0
14
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
7
0
0
0
14
7
7
7
0
% K
% Leu:
7
7
0
0
7
0
7
7
7
0
40
0
0
7
14
% L
% Met:
0
0
7
0
0
0
0
0
0
7
0
14
7
0
0
% M
% Asn:
27
0
0
0
34
14
0
7
0
20
7
20
0
0
7
% N
% Pro:
7
40
14
0
20
0
7
7
0
0
7
7
14
0
7
% P
% Gln:
0
7
0
7
7
7
0
0
7
7
0
0
7
7
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
20
27
7
0
0
0
7
7
7
14
7
14
0
14
0
% S
% Thr:
0
0
34
7
7
7
7
40
40
0
0
0
0
0
7
% T
% Val:
0
7
20
7
0
0
0
7
7
0
14
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _