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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC13A1 All Species: 42.12
Human Site: S452 Identified Species: 77.22
UniProt: Q9BZW2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZW2 NP_071889.2 595 66134 S452 L A D G C E E S G L S K W I G
Chimpanzee Pan troglodytes XP_519338 595 65911 S452 L A D G C E E S G L S K W I G
Rhesus Macaque Macaca mulatta XP_001085242 595 65945 S452 L A D G C E E S G L S N W I G
Dog Lupus familis XP_539548 596 65560 S453 L A D G C E E S G L S K W I G
Cat Felis silvestris
Mouse Mus musculus Q9JHI4 594 66036 S451 L A D G C Q V S G L S N W I G
Rat Rattus norvegicus Q07782 595 66041 S452 L A D G C Q V S G L S S W I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507053 642 69742 S491 L A K G S E V S G L S S W L G
Chicken Gallus gallus XP_001233531 628 69367 S455 L A D G C E V S K L S A W V A
Frog Xenopus laevis NP_001079687 601 66475 S456 L A K G C E V S G L S T W V G
Zebra Danio Brachydanio rerio NP_954975 583 63943 S441 L A E G T K I S G L S S W V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVT2 590 65567 S442 L A E G S K Q S G M A K L I G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93655 582 64168 S422 L A A G V K E S G L S H D I G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LG88 540 58080 V414 R T S G L A E V L S K G L V F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.9 86.7 N.A. 80.8 82.8 N.A. 42.9 69.7 52.5 54.4 N.A. 27 N.A. 35.9 N.A.
Protein Similarity: 100 98.6 96.8 91.1 N.A. 89.7 90.7 N.A. 62.7 80.4 69.3 72.7 N.A. 49.5 N.A. 57.4 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 80 80 N.A. 66.6 66.6 73.3 53.3 N.A. 53.3 N.A. 66.6 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 86.6 N.A. 73.3 73.3 80 73.3 N.A. 86.6 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 93 8 0 0 8 0 0 0 0 8 8 0 0 16 % A
% Cys: 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 54 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 16 0 0 54 47 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 100 0 0 0 0 85 0 0 8 0 0 77 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 62 0 % I
% Lys: 0 0 16 0 0 24 0 0 8 0 8 31 0 0 0 % K
% Leu: 93 0 0 0 8 0 0 0 8 85 0 0 16 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 16 8 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 16 0 0 93 0 8 85 24 0 0 0 % S
% Thr: 0 8 0 0 8 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 8 0 39 8 0 0 0 0 0 31 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 77 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _