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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM6SF2
All Species:
21.52
Human Site:
S165
Identified Species:
47.33
UniProt:
Q9BZW4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZW4
NP_001001524.2
351
39574
S165
G
N
I
L
G
K
Y
S
S
E
I
R
P
A
F
Chimpanzee
Pan troglodytes
XP_001140342
351
39569
S165
G
N
I
L
G
K
Y
S
S
E
I
R
P
A
F
Rhesus Macaque
Macaca mulatta
XP_001115169
351
39412
S165
G
N
I
L
G
K
Y
S
S
E
I
R
P
A
F
Dog
Lupus familis
XP_852125
376
42581
S165
G
N
I
L
G
K
Y
S
S
E
V
R
P
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1J1
378
43008
S165
G
N
I
L
G
K
Y
S
S
E
M
R
P
T
F
Rat
Rattus norvegicus
NP_001121126
378
42556
S165
G
N
I
L
G
K
Y
S
S
E
I
R
P
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513106
345
39369
R162
M
R
I
F
S
Q
P
R
A
L
P
C
C
S
P
Chicken
Gallus gallus
XP_413840
370
41520
G164
G
N
I
V
G
K
Y
G
T
K
V
C
P
A
F
Frog
Xenopus laevis
Q6DCP8
370
41347
G164
G
N
I
V
G
K
Y
G
T
R
I
C
S
A
L
Zebra Danio
Brachydanio rerio
NP_001074130
374
42382
G162
G
I
V
V
G
K
Y
G
S
E
I
R
P
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793469
381
42849
G166
G
N
V
S
G
K
Y
G
S
N
V
K
G
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.3
77.3
N.A.
73.5
73.5
N.A.
64.3
48.3
45.6
41.7
N.A.
N.A.
N.A.
N.A.
39.6
Protein Similarity:
100
99.7
98
83.7
N.A.
81.2
80.9
N.A.
74
65.1
60.2
59
N.A.
N.A.
N.A.
N.A.
55.1
P-Site Identity:
100
100
100
80
N.A.
86.6
93.3
N.A.
6.6
60
53.3
73.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
26.6
86.6
66.6
86.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
28
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
64
% F
% Gly:
91
0
0
0
91
0
0
37
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
82
0
0
0
0
0
0
0
55
0
0
0
0
% I
% Lys:
0
0
0
0
0
91
0
0
0
10
0
10
0
0
0
% K
% Leu:
0
0
0
55
0
0
0
0
0
10
0
0
0
0
19
% L
% Met:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
82
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
10
0
73
0
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
10
0
64
0
0
0
% R
% Ser:
0
0
0
10
10
0
0
55
73
0
0
0
10
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
19
0
0
0
0
28
0
% T
% Val:
0
0
19
28
0
0
0
0
0
0
28
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _