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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM6SF2
All Species:
8.79
Human Site:
S341
Identified Species:
19.33
UniProt:
Q9BZW4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZW4
NP_001001524.2
351
39574
S341
F
F
H
Q
P
P
P
S
D
P
L
A
L
H
K
Chimpanzee
Pan troglodytes
XP_001140342
351
39569
S341
F
F
H
Q
P
P
P
S
D
P
L
A
L
H
K
Rhesus Macaque
Macaca mulatta
XP_001115169
351
39412
S341
F
F
H
Q
P
P
P
S
S
P
I
A
L
H
K
Dog
Lupus familis
XP_852125
376
42581
L341
A
S
F
F
G
Y
N
L
L
Y
A
L
G
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1J1
378
43008
L341
A
T
F
F
L
S
N
L
L
L
A
L
G
P
H
Rat
Rattus norvegicus
NP_001121126
378
42556
L341
A
T
F
L
L
S
N
L
L
F
A
L
G
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513106
345
39369
H335
F
F
L
N
P
G
P
H
R
Q
E
G
E
D
K
Chicken
Gallus gallus
XP_413840
370
41520
I340
Q
F
F
L
I
L
N
I
M
Y
G
I
L
P
Q
Frog
Xenopus laevis
Q6DCP8
370
41347
I340
I
F
F
F
T
A
N
I
L
F
G
L
G
S
Q
Zebra Danio
Brachydanio rerio
NP_001074130
374
42382
L338
L
S
V
L
L
L
N
L
L
Y
A
V
G
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793469
381
42849
M341
S
A
F
W
L
I
N
M
A
L
L
L
V
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.3
77.3
N.A.
73.5
73.5
N.A.
64.3
48.3
45.6
41.7
N.A.
N.A.
N.A.
N.A.
39.6
Protein Similarity:
100
99.7
98
83.7
N.A.
81.2
80.9
N.A.
74
65.1
60.2
59
N.A.
N.A.
N.A.
N.A.
55.1
P-Site Identity:
100
100
86.6
0
N.A.
0
0
N.A.
33.3
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
0
N.A.
0
0
N.A.
33.3
20
13.3
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
0
10
0
0
10
0
37
28
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
19
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
37
55
55
28
0
0
0
0
0
19
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
19
10
46
0
0
% G
% His:
0
0
28
0
0
0
0
10
0
0
0
0
0
28
28
% H
% Ile:
10
0
0
0
10
10
0
19
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% K
% Leu:
10
0
10
28
37
19
0
37
46
19
28
46
37
0
0
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
64
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
37
28
37
0
0
28
0
0
0
55
0
% P
% Gln:
10
0
0
28
0
0
0
0
0
10
0
0
0
0
28
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
19
0
0
0
19
0
28
10
0
0
0
0
10
0
% S
% Thr:
0
19
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
28
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _