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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TM6SF1 All Species: 38.18
Human Site: Y263 Identified Species: 84
UniProt: Q9BZW5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZW5 NP_001138375.1 370 41636 Y263 Y L K D P A A Y P K I Q M L A
Chimpanzee Pan troglodytes XP_510557 371 41677 Y264 Y L K D P A A Y P K I Q M L A
Rhesus Macaque Macaca mulatta XP_001088546 374 42104 Y267 Y L K D P A A Y P K I Q M L A
Dog Lupus familis XP_536207 385 43331 Y278 Y L K D P A A Y P K I Q M L A
Cat Felis silvestris
Mouse Mus musculus P58749 370 41630 Y263 Y L K D P A A Y P K I Q M L A
Rat Rattus norvegicus NP_001101960 345 39152 Y238 Y L K D P A A Y P K I Q M L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513106 345 39369 Y232 Y L R D P V A Y P K V Q M L V
Chicken Gallus gallus XP_413840 370 41520 Y263 Y I K D P A A Y P K L Q M L A
Frog Xenopus laevis Q6DCP8 370 41347 Y263 Y I K D P S A Y P K L Q M L V
Zebra Danio Brachydanio rerio NP_001074130 374 42382 F261 Y L K D P V G F P K V M M L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793469 381 42849 Y264 Y F Q D P V L Y P M I Q A L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 90.9 86.7 N.A. 94.5 87 N.A. 49.1 80.5 68.1 43.8 N.A. N.A. N.A. N.A. 47.7
Protein Similarity: 100 99.4 92.2 90.1 N.A. 97.8 90.8 N.A. 67.8 89.7 81 63.3 N.A. N.A. N.A. N.A. 64.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 86.6 73.3 60 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 100 93.3 73.3 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 64 82 0 0 0 0 0 10 0 64 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 19 0 0 0 0 0 0 0 0 64 0 0 0 0 % I
% Lys: 0 0 82 0 0 0 0 0 0 91 0 0 0 0 0 % K
% Leu: 0 73 0 0 0 0 10 0 0 0 19 0 0 100 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 10 91 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 100 0 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 91 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 28 0 0 0 0 19 0 0 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 100 0 0 0 0 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _