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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: API5 All Species: 34.55
Human Site: S341 Identified Species: 84.44
UniProt: Q9BZZ5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZZ5 NP_001136402.1 510 57561 S341 E E P K L Q F S Y V E C L L Y
Chimpanzee Pan troglodytes XP_508375 510 57543 S341 E E P K L Q F S Y V E C L L Y
Rhesus Macaque Macaca mulatta XP_001114443 510 57374 S341 E E P K L Q F S Y V E C L L Y
Dog Lupus familis XP_540533 510 57511 S341 E E P K L Q F S Y V E C L L Y
Cat Felis silvestris
Mouse Mus musculus O35841 504 56753 N333 E N G E N A G N E E P K L Q F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509256 524 58877 S341 E E P K L Q F S Y V E C L L Y
Chicken Gallus gallus Q5ZMW3 523 58591 S341 E E P K L Q F S Y V E C L L Y
Frog Xenopus laevis Q7ZY79 523 58614 S341 E E P K L Q F S Y V E C L L F
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V431 536 59912 S345 T P P S F Q F S H A E C L L Y
Honey Bee Apis mellifera XP_624077 529 60341 S336 E V P Q L Q F S H V E C L M Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99.6 98.6 N.A. 96.2 N.A. N.A. 93.3 91.7 82.4 N.A. N.A. 44.5 48.5 N.A. N.A.
Protein Similarity: 100 100 99.6 99.4 N.A. 97 N.A. N.A. 95 93.8 90.4 N.A. N.A. 62.8 70.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 N.A. N.A. 100 100 93.3 N.A. N.A. 60 73.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 33.3 N.A. N.A. 100 100 100 N.A. N.A. 66.6 93.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 90 70 0 10 0 0 0 0 10 10 90 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 90 0 0 0 0 0 0 0 20 % F
% Gly: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 70 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 0 80 0 0 0 0 0 0 0 100 80 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 0 0 10 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 10 90 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 10 0 90 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 0 90 0 0 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 80 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 70 0 0 0 0 0 80 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _