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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
API5
All Species:
20.3
Human Site:
S457
Identified Species:
49.63
UniProt:
Q9BZZ5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZZ5
NP_001136402.1
510
57561
S457
E
I
G
Q
K
R
A
S
E
D
T
T
S
G
S
Chimpanzee
Pan troglodytes
XP_508375
510
57543
S457
E
I
G
Q
K
R
A
S
E
D
T
T
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001114443
510
57374
S457
E
I
G
Q
K
R
A
S
E
D
T
T
S
G
S
Dog
Lupus familis
XP_540533
510
57511
N457
E
I
G
Q
K
R
A
N
E
D
T
T
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
O35841
504
56753
E450
W
K
P
V
Q
K
V
E
I
G
Q
K
R
T
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509256
524
58877
S457
E
S
G
Q
K
R
A
S
E
D
T
S
S
G
S
Chicken
Gallus gallus
Q5ZMW3
523
58591
S457
D
A
N
Q
K
R
T
S
E
D
T
T
S
S
S
Frog
Xenopus laevis
Q7ZY79
523
58614
S457
D
S
G
Q
K
R
M
S
D
E
T
S
S
T
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V431
536
59912
P461
K
L
G
K
R
H
A
P
I
T
F
G
E
K
A
Honey Bee
Apis mellifera
XP_624077
529
60341
P450
S
A
Q
K
R
H
T
P
I
T
F
G
N
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.6
98.6
N.A.
96.2
N.A.
N.A.
93.3
91.7
82.4
N.A.
N.A.
44.5
48.5
N.A.
N.A.
Protein Similarity:
100
100
99.6
99.4
N.A.
97
N.A.
N.A.
95
93.8
90.4
N.A.
N.A.
62.8
70.1
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
6.6
N.A.
N.A.
86.6
66.6
53.3
N.A.
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
N.A.
N.A.
93.3
73.3
80
N.A.
N.A.
46.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
60
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
10
60
0
0
0
10
0
% D
% Glu:
50
0
0
0
0
0
0
10
60
10
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% F
% Gly:
0
0
70
0
0
0
0
0
0
10
0
20
0
50
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
40
0
0
0
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
10
10
0
20
70
10
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
70
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
20
70
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
20
0
0
0
0
0
60
0
0
0
20
70
10
90
% S
% Thr:
0
0
0
0
0
0
20
0
0
20
70
50
0
20
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _