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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT23
All Species:
9.39
Human Site:
S389
Identified Species:
22.96
UniProt:
Q9C075
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C075
NP_056330.3
422
48131
S389
T
R
E
E
S
K
S
S
M
K
V
S
A
T
P
Chimpanzee
Pan troglodytes
A5A6M0
432
48102
P402
L
T
Q
Y
K
K
E
P
V
T
T
R
Q
V
R
Rhesus Macaque
Macaca mulatta
XP_001101954
422
48072
S389
T
M
E
E
S
K
S
S
M
K
A
S
A
T
P
Dog
Lupus familis
XP_548125
422
48205
S389
T
M
E
E
S
K
S
S
V
K
V
S
W
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99PS0
422
48008
R389
T
M
D
G
S
E
S
R
L
K
G
S
E
A
S
Rat
Rattus norvegicus
Q6IFU7
452
50195
S412
L
A
T
Q
Y
S
S
S
L
A
S
Q
A
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520563
418
47025
K388
G
M
D
D
S
K
S
K
S
T
K
S
A
A
P
Chicken
Gallus gallus
O93256
423
46064
R395
E
Q
E
I
A
T
Y
R
Q
L
L
E
G
Q
E
Frog
Xenopus laevis
P08778
433
47788
K392
F
S
Q
T
E
T
Q
K
A
V
T
I
V
S
K
Zebra Danio
Brachydanio rerio
NP_001002383
438
49767
E397
R
Q
T
I
K
V
V
E
V
V
A
P
P
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.1
95.2
80.8
N.A.
78.9
40.4
N.A.
63
42.5
37.8
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.3
97.1
90.7
N.A.
88.8
62.1
N.A.
77.7
64.5
60.7
64.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
66.6
N.A.
33.3
20
N.A.
40
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
86.6
80
N.A.
53.3
40
N.A.
53.3
26.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
10
10
20
0
40
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
40
30
10
10
10
10
0
0
0
10
10
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
20
50
0
20
0
40
10
0
0
10
10
% K
% Leu:
20
0
0
0
0
0
0
0
20
10
10
0
0
0
0
% L
% Met:
0
40
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
40
% P
% Gln:
0
20
20
10
0
0
10
0
10
0
0
10
10
10
0
% Q
% Arg:
10
10
0
0
0
0
0
20
0
0
0
10
0
0
20
% R
% Ser:
0
10
0
0
50
10
60
40
10
0
10
50
0
30
10
% S
% Thr:
40
10
20
10
0
20
0
0
0
20
20
0
0
20
10
% T
% Val:
0
0
0
0
0
10
10
0
30
20
20
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _