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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPEF2 All Species: 9.09
Human Site: T1527 Identified Species: 28.57
UniProt: Q9C093 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C093 NP_079143.3 1822 209811 T1527 Q E L T S L L T V N S E F V D
Chimpanzee Pan troglodytes XP_526950 883 102233 H637 K E S Q D P Q H V F S A G P V
Rhesus Macaque Macaca mulatta XP_001091802 888 102978 G642 P Q N V F S A G P V S N E V L
Dog Lupus familis XP_546353 1821 210286 I1528 Q E L T S L V I V N S E F V D
Cat Felis silvestris
Mouse Mus musculus Q8C9J3 1734 199126 T1441 Q E I T S L L T V N T E F V D
Rat Rattus norvegicus Q9R095 1801 208141 T1508 Q E I T S L L T V N T E F V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509349 1601 184534 I1331 A H F L L D V I N V L G I L S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121704 1639 188212 A1372 E E L V C I L A Q D S E M L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.7 46.7 82.1 N.A. 70.6 73.2 N.A. 25.9 N.A. N.A. 36.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 48.2 48.1 91.1 N.A. 82.4 84.5 N.A. 42 N.A. N.A. 55.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 13.3 86.6 N.A. 86.6 86.6 N.A. 0 N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 20 93.3 N.A. 100 100 N.A. 13.3 N.A. N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 13 13 0 0 0 13 0 0 0 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 13 0 0 0 13 0 0 0 0 63 % D
% Glu: 13 75 0 0 0 0 0 0 0 0 0 63 13 0 0 % E
% Phe: 0 0 13 0 13 0 0 0 0 13 0 0 50 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 13 13 0 0 % G
% His: 0 13 0 0 0 0 0 13 0 0 0 0 0 0 0 % H
% Ile: 0 0 25 0 0 13 0 25 0 0 0 0 13 0 0 % I
% Lys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 38 13 13 50 50 0 0 0 13 0 0 25 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 13 0 0 0 0 0 13 50 0 13 0 0 0 % N
% Pro: 13 0 0 0 0 13 0 0 13 0 0 0 0 13 0 % P
% Gln: 50 13 0 13 0 0 13 0 13 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 13 0 50 13 0 0 0 0 63 0 0 0 13 % S
% Thr: 0 0 0 50 0 0 0 38 0 0 25 0 0 0 0 % T
% Val: 0 0 0 25 0 0 25 0 63 25 0 0 0 63 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _