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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD5 All Species: 19.39
Human Site: S683 Identified Species: 53.33
UniProt: Q9C0A6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0A6 NP_001073986.1 1442 157515 S683 G S D P T V V S I T G S H V N
Chimpanzee Pan troglodytes XP_516258 1426 155894 T678 P L T G S D P T V V S I T G S
Rhesus Macaque Macaca mulatta XP_001092500 1474 160966 S715 G S D P T V V S I T G S H V N
Dog Lupus familis XP_862248 1437 157122 S681 G S D P T V L S V T G S H V N
Cat Felis silvestris
Mouse Mus musculus Q5XJV7 1441 157407 S683 G S D P T V I S V T G S H V N
Rat Rattus norvegicus NP_001100084 1446 158264 S688 G S D P T V V S V T G S H V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508126 1444 158267 L684 G S D P V A T L A T G T Q V N
Chicken Gallus gallus XP_001233428 1446 157725 Q696 E G P G E G R Q L M G S D P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_698834 1471 160208 H722 E G A P N C G H L Q D G E L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 97.2 95.1 N.A. 94.1 92.8 N.A. 72.2 74 N.A. 44.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.8 97.4 96.8 N.A. 96.5 95.5 N.A. 80.8 82.1 N.A. 57.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 86.6 N.A. 86.6 93.3 N.A. 53.3 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 60 20 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 12 0 0 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 12 0 0 0 0 12 0 12 0 0 % D
% Glu: 23 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 67 23 0 23 0 12 12 0 0 0 78 12 0 12 0 % G
% His: 0 0 0 0 0 0 0 12 0 0 0 0 56 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 23 0 0 12 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 0 0 0 12 12 23 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 67 % N
% Pro: 12 0 12 78 0 0 12 0 0 0 0 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 12 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % R
% Ser: 0 67 0 0 12 0 0 56 0 0 12 67 0 0 12 % S
% Thr: 0 0 12 0 56 0 12 12 0 67 0 12 12 0 12 % T
% Val: 0 0 0 0 12 56 34 0 45 12 0 0 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _