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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD5
All Species:
22.73
Human Site:
Y755
Identified Species:
62.5
UniProt:
Q9C0A6
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0A6
NP_001073986.1
1442
157515
Y755
I
C
T
T
P
K
H
Y
I
R
F
G
S
P
F
Chimpanzee
Pan troglodytes
XP_516258
1426
155894
P744
L
P
G
L
I
H
S
P
L
I
C
T
T
P
K
Rhesus Macaque
Macaca mulatta
XP_001092500
1474
160966
Y787
I
C
T
T
P
K
H
Y
I
R
F
G
S
P
F
Dog
Lupus familis
XP_862248
1437
157122
Y753
I
C
T
T
P
K
H
Y
I
R
F
G
S
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJV7
1441
157407
Y755
I
C
T
T
P
K
H
Y
I
R
F
G
S
P
F
Rat
Rattus norvegicus
NP_001100084
1446
158264
Y760
I
C
T
T
P
K
H
Y
I
R
F
G
S
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508126
1444
158267
Y756
I
C
T
T
P
K
H
Y
V
R
F
G
S
P
Y
Chicken
Gallus gallus
XP_001233428
1446
157725
P763
A
T
T
L
N
M
L
P
G
L
I
H
S
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698834
1471
160208
P789
A
T
T
L
N
M
L
P
G
L
S
H
S
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
97.2
95.1
N.A.
94.1
92.8
N.A.
72.2
74
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.8
97.4
96.8
N.A.
96.5
95.5
N.A.
80.8
82.1
N.A.
57.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
86.6
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
67
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
56
% F
% Gly:
0
0
12
0
0
0
0
0
23
0
0
67
0
0
0
% G
% His:
0
0
0
0
0
12
67
0
0
0
0
23
0
0
0
% H
% Ile:
67
0
0
0
12
0
0
0
56
12
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
12
% K
% Leu:
12
0
0
34
0
0
23
0
12
23
0
0
0
0
23
% L
% Met:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
67
0
0
34
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
12
0
0
0
12
0
89
0
0
% S
% Thr:
0
23
89
67
0
0
0
0
0
0
0
12
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _